Results 151 to 160 of about 1,182,326 (304)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Nurses Exploring the Spirituality of Their Patients With Cancer: Participant Observation on a Medical Oncology Ward. [PDF]

Cancer Nurs, 2018
van Meurs J, Smeets W, Vissers KCP, Groot M, Engels Y.   +4 more
europepmc   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Implementing an Oral Health Intervention for People Experiencing Homelessness in Scotland: A Participant Observation Study. [PDF]

Dent J (Basel), 2018
Beaton L, Anderson I, Humphris G, Rodriguez A, Freeman R.   +4 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Les pratiques de terrain en situation de tensions sociales et de guerre civile au Congo-Brazzaville

Sociologies, 2011
Referring to my own field practices in a situation of social tension and civil war in Congo-Brazzaville entails a genuine critical examination of a society which is at the same time a social world made up of a plurality of social microcosms and the field
Abel Kouvouama
doaj  

Enabling At-Homeness for Older People With Life-Limiting Conditions: A Participant Observation Study From Nursing Homes. [PDF]

Glob Qual Nurs Res, 2019
Saarnio L, Boström AM, Hedman R, Gustavsson P, Öhlén J.   +4 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Fostering Reflective Practice Through Participant Observation: Medical Students' Learning During Community-Based Clinical Training in Japan. [PDF]

Yonago Acta Med
Kamimoto M, Son D, Inoue K, Imaoka S, Nakai T, Otsuka Y, Taniguchi S, Taniguchi SI.   +7 more
europepmc   +1 more source