Results 161 to 170 of about 1,182,326 (304)

How are decisions made in cancer care? A qualitative study using participant observation of current practice. [PDF]

BMJ Open, 2017
Hahlweg P, Härter M, Nestoriuc Y, Scholl I.   +3 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The emotional toll of day-of-surgery cancellations on patients - a qualitative study using participant observation and interviews. [PDF]

Int J Qual Stud Health Well-being
Viftrup A, Nikolajsen L, Laustsen S, Dreyer P.   +3 more
europepmc   +1 more source

Support provided by midwives to women during labour in a public hospital, Limpopo Province, South Africa: a participant observation study. [PDF]

BMC Pregnancy Childbirth, 2018
Maputle MS.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Menstrual health practices among Tibetan women: An ethnographic participant observation study. [PDF]

J Family Med Prim Care
Dhadwal Y, Kumar A, Pandey SR.
europepmc   +1 more source

Challenges of introducing participant observation to community health research. [PDF]

ISRN Nurs, 2014
Zhao M, Ji Y.
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Compliance with infection control practices among healthcare workers in radiology departments: a participant observation study and adenosine triphosphate assay evaluation of environmental cleanliness. [PDF]

Infect Prev Pract
Lau LHW, Tse FWF, Suen LKP, Lam SC.
europepmc   +1 more source

Which user errors matter during HIV self-testing? A qualitative participant observation study of men who have sex with men (MSM) in China. [PDF]

BMC Public Health, 2018
Wei C, Yan L, Li J, Su X, Lippman S, Yan H.   +5 more
europepmc   +1 more source