Results 131 to 140 of about 6,140,428 (291)

The Effects of the MONOZUKURI Program on Executive Function Among Community‐Dwelling Older Adults: A Randomized Controlled Trial

open access: yesBrain and Behavior
Introduction This study aimed to examine the effect of the MONOZUKURI program, a cognitive intervention related to creative activities (handicrafts and creative cooking), on cognitive function in community‐dwelling older adults.
Ai Iizuka   +8 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The Problem of Women and Mathematics [PDF]

open access: yes, 1981
Reviews relevant research to determine the reasons for the limited participation of women in advanced mathematics and related fields. Explores options for improving women's mathematics skills and increasing their participation in related ...
Lynn H. Fox
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Physical, psychological, and social factors related to help-seeking preferences among older adults living in a community

open access: yesBMC Public Health
Background Examining the nature of help seeking and related factors among community-dwelling older adults is important to address social problems, such as loneliness and consumer damage.
Tomoya Takahashi   +9 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Overcoming Participation Constraints [PDF]

open access: yes
In incomplete information environments with transferable utility, efficient outcomes are generally implementable unless interim or ex post participation constraints are imposed on the problem.
Hanming Fang, Peter Norman
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Participation for what: social change or social control? [PDF]

open access: yes, 2010
The publication is special, both content-wise and process-wise, as it is entirely produced by (alumni and present) ISS PhD students, and Open Acces available.
Corradi, A.A. (Ariane Agnes)   +3 more
core  

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