Results 151 to 160 of about 6,031,064 (343)
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker+9 more
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin+2 more
wiley +1 more source
AbstractA notion of “participation” of a subset S in a countable set U is investigated. Such a notion is needed to express the approximate behavior of computations. Different measures are proposed and their properties derived. Finally one particular measure associated with the density of points of S in U is shown to be both intuitively appealing and ...
openaire +2 more sources
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
An investigation into the factors affecting second language learners’ classroom participation [PDF]
This study was conducted to identify the second language learners' perceptions of their classroom participation. Factors influencing the learners' classroom participation were also examined.
Liew, Hui Choo, Mohamad Nor, Faizah
core
Scales for measuring attitudes toward participation in decisions about uses of family income
Gladys Winifred Babcock
openalex +2 more sources
PARTICIPATION OF VITAMIN B6 IN THE BIOSYNTHESIS OF COENZYME A
Kozo Yamada+2 more
openalex +2 more sources