Results 61 to 70 of about 9,995 (264)
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Recently, researchers have deployed the Theory of Planned Behavior (TPB) to examine factors influencing financial inclusion participation behaviour. However, more must be made to expand the theory by integrating sectoral and contextual variables.
Haruna Musa +2 more
doaj +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
This study examines the adoption of Islamic banking (Participation banking) mobile applications in Turkey within the framework of the Unified Theory of Acceptance and Use of Technology (UTAUT).
Yunus Kutval
doaj +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Katılım Bankaları ve TCMB Arasında Likidite Yönetimi: Bir Depo Alım Modeli Önerisi
Katılım bankacılığı sektörünün Türkiye Cumhuriyet Merkez Bankası (TCMB) nezdinde depo (mevduat veya plasman) alımına ilişkin mevcut imkânlarının kısıtlı olması nedeniyle, katılım bankaları fazla likiditelerini konvansiyonel bankalar kadar etkin ve kârlı ...
Fatih Kazancı
doaj +1 more source
Participation of non-banking financial organisations in crediting innovation projects [PDF]
The article describes main results of study of non-banking financial institutions as creditors of innovation projects. Based on the analysis of their investment activity, the article identifies their place and role in financing innovations.
Duba Olexandr M. +2 more
doaj
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source

