Results 151 to 160 of about 21,203 (262)

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Pulse of Generosity: A Qualitative Insight Into the Knowledge, Attitudes, and Motivations of Voluntary Blood Donors at a Tertiary Care Hospital, Maldives. [PDF]

Biomed Res Int
Khadeeja, Selna A, Yoosuf AK.
europepmc   +1 more source

INDICATORS OF PREFERENCE FOR PARTICIPATION BANKING: A RESEARCH ON PEOPLE WHO DO NOT USE PARTICIPATION BANKING IN THEIR FINANCIAL TRANSACTIONS [PDF]

International Journal of Business Economics and Management Perspectives, 2020
openaire   +1 more source

Understanding the Catalytic Determinant role of Diaphorase‐Like Subunit in Formate Dehydrogenases via Redox Couples

Advanced Science, EarlyView.
A unique mechanism of catalytic bias regulated by diaphorase‐like subunit in formate dehydrogenase from Rhodobacter aestuarii is revealed. The diaphorase‐like subunit functions act as a biological “voltage rheostat” that controls the slow release of NADH to regulate redox balance, biasing the enzyme's catalytic preference toward CO2 reduction over ...
Kuncheng Zhang, Weisong Liu, Hao Su, Huijuan Cui, Yuanming Wang, Zhiguang Zhu, Chun You, Lingling Zhang   +7 more
wiley   +1 more source

m-Lifestyle Intervention for Employees (m-LIfE): protocol for a pilot cluster randomized controlled trial on cardiovascular disease prevention strategies. [PDF]

Pilot Feasibility Stud
Akhtar S, Samad Z, Bloomfield GS, Ajani K, Virani SS, Awan S, Almas A.   +6 more
europepmc   +1 more source

Stretchable Microelectrode Arrays with Microneedles for Reliable Electrophysiological Recording of Human Heart and Brain Organoids

Advanced Science, EarlyView.
A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang, Saewoon Shin, Seul‐Gi Lee, Kiup Kim, Yoojeong Kim, Jun Sun, Il‐Joo Cho, Joseph A. Gogos, Jong‐Chan Park, C‐Yoon Kim, Hyunjoo J. Lee   +10 more
wiley   +1 more source

Cyber Risk Management of API-Enabled Financial Crime in Open Banking Services. [PDF]

Entropy (Basel)
Ojehomon OG, Cichorska J, Michnik J.
europepmc   +1 more source

Functioning of state participating banks at the market of bank services of Ukraine

Scientific Horizons, 2019
L. Sus, M. Onychuk
openaire   +1 more source

Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review

Advanced Science, EarlyView.
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh, Ki‐bum Lee, Junghyeon Lee, Seunghee Cho, Malkeshkumar Patel, Hangfei Li, Yu Wen, Ye Zhou, Joondong Kim   +8 more
wiley   +1 more source

Developing the future clinical research workforce: An immersive high school clinical research summer camp. [PDF]

J Clin Transl Sci
Fritter JM, Banks T, Harmon M, Sasindran S, Tadros S, Spacht DE, Carter KK, Fannin K, Jones L, Jones CT.   +9 more
europepmc   +1 more source