AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz +4 more
wiley +1 more source
Editorial: Community engagement: models and effectiveness. [PDF]
Swider SM, Edwards L, Bejster M.
europepmc +1 more source
Extreme‐Thickness Meta‐Membrane for Controlling Terahertz Vectorial Beams
We propose ultra‐thin (λ/30) transmissive terahertz metasurfaces combining near‐field resonant and detour phases in coupled‐slit meta‐atoms, enabling continuous phase and polarization control beyond conventional designs. Based on leaky‐mode theory, scalar and vectorial terahertz Bessel beams at 0.39 THz are experimentally demonstrated, with ...
Yufei Song +7 more
wiley +1 more source
Making economic citizens beyond neoliberalism: Historical trajectories of a banker association's efforts in economic education. [PDF]
Ruoss T.
europepmc +1 more source
PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
Cybersecurity Awareness as a Mediating Variable in the Relationship between ICS and AIS in Iraqi State Banks. [PDF]
Ahmed Al-Mohammedi Y +3 more
europepmc +1 more source
A biomimetic artificial extracellular matrix is assembled directly on Pseudomonas fluorescens by co‐assembling amyloid‐like lysozyme and alginate at the cell surface. This conformal nanocoating acts as both a hydration buffer and a physiological priming layer, markedly enhancing desiccation tolerance, seed adhesion, storage stability, and biocontrol ...
Yuanyuan Wang +5 more
wiley +1 more source
Restoration Contexts and Trends in the Brazilian Atlantic Forest: Evidence from Science and Practice. [PDF]
Oliveira SC +3 more
europepmc +1 more source
A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley +1 more source
The impact of government macroeconomic policies and elections on income smoothing in state-controlled commercial banks: Evidence from the MENA region. [PDF]
Peykani P +4 more
europepmc +1 more source

