Results 81 to 90 of about 803,885 (335)
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Descentralização e endividamento municipal: formas, limites e possibilidades
Decentralization and municipal indebtedness: modes, constraints, and possibilities [PDF]
Nova Economia, 2002 The objective of this article is to discuss alternatives to finance investments by municipalities. In general, current revenues are insufficient to finance large investments, what brings about the necessity of municipal indebtedness.
Amaury Patrick Gremaud +1 more
doaj
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
The Governance of Climate Change Adaptation Finance—An Overview and Critique
Revue Internationale de Politique de Développement, 2019 At COP21 in Paris parties to the UNFCCC reiterated the goal of USD 100 billion annually in climate finance by 2020 and agreed to set a more ambitious target by 2025.
Morgan Scoville-Simonds
doaj +1 more source
Community programs and women's participation : the Chinese experience [PDF]
Using household data specifically collected for the purpose of evaluation, the authors empirically evaluate the impact on household income of a rural program in China that focuses on increasing women's economic and social participation in the local ...
Coady, David, Limin Wang, Xinyi Dai
core
FEBS Open Bio, EarlyView.Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal +2 more
wiley +1 more source
Gender, generations, and nonfarm participation [PDF]
The authors present an empirical analysis of intergenerational links in nonfarm participation with a focus on gender effects. Using survey data from Nepal, the evidence shows that the mother exerts a strong influence on a daughter's employment choice ...
Emran, M. Shabe +2 more
core
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
How fair is workfare? gender, public works, and employment in rural Ethiopia [PDF]
The authors use the Ethiopian Rural Household Survey to examine the gender dimensions of public works. They use three rounds of a panel conducted in 1994-95 to explore the determinants of participation in, days worked, wages, and earnings from wage labor,
Quisumbing, Agnes R., Yohannes, Yisehac
core
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source