Results 91 to 100 of about 10,692,737 (296)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Gendered effects of work and participation in collective forest management [PDF]
This paper reports the results of a statistical investigation of the relationship between labor time expended in rural livelihoods, social structure, and community forest management.
Naidu, Sirisha C.
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FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Maklews Etnic Woman’s Participation on Environmental Management
E3S Web of Conferences, 2018 Woman have strong links with the environmental. In his role as manager of the household, they are more interacting with the environmental and natural recousces.The efforts were made by Maklew’s Woman with cultivated an attitude of assistance and keep ...
Samderubun Godefridus +3 more
doaj +1 more source
Conflict management approaches, customer expectation evaluation, and customer satisfaction : an empirical investigation [PDF]
, 2004 vii, 71 leaves ; 29 cm.This study investigates the potential impacts of different conflict management approaches and expectation evaluation on customer satisfaction.
University of Lethbridge. Faculty of Management +1 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
EMPLOYEE PARTICIPATION IN EUROPE [PDF]
The goal of this study was to identify the determinants of employee participation in organizations across Europe. Power distance, uncertainty avoidance, competition, unionisation, sector, organizational size and business strategy were all expected to ...
Ángel Cabrera +2 more
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Voluntary participation in community collaborative forest management: A case study of Central Java, Indonesia [PDF]
, 2012 This paper examines voluntary participation in community forest management, and characterizes how more participation may be induced. We implemented a survey of 571 respondents and conducted a case study in Central Java, Indonesia.
Lestari, Sri +12 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source