Results 41 to 50 of about 44,053 (222)

Increasing Ramadan Activities Through the Participatory Action Research

open access: yesAl-Arkhabiil, 2023
The implementation of this research focuses on realizing that the community understands the basics of the Islamic Religion, assisting parents in educating the Muslim generation to love the Qur'an and Arabic.
Arbonas Lubis   +4 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Inclusion of Community-Based Participatory Research in High-Impact Medical Journals

open access: yesHealth Equity
Community-based participatory research (CBPR) is essential for addressing health care inequities; however, it is unclear to what extent articles published in high-impact medical journals use CPBR.
Michelle Doughtery   +9 more
doaj   +1 more source

In memory of master Orlando falls Borda: basis and development of participatory action research in Cordoba (Colombia)

open access: yesInternational Journal of Psychological Research, 2008
On March 6, 1972, sociologist Orlando Fals Borda, a native of Barranquilla, arrived in Monteria. He was commissioned by the Rosca Foundation for Research and Social Action to work on the Coast, based in Monteria.
Victor Negrete
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

UTILITATEA ŞI RELEVANŢA CERCETĂRII PARTICIPATIVE ÎN INVESTIGAREA FENOMENELOR SOCIALE

open access: yesStudia Universitatis Moldaviae: Stiinte Sociale, 2017
În acest articol este luată în vizor o nouă paradigmă de cercetare a fenomenelor sociale, care pune accentul pe abor­darea participativă: actorii sociali studiaţi devin membri ai echipelor de cercetare, favorizând cunoaşterea din interior şi aprofundată ...
Anastasia OCERETNÎI
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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