Results 81 to 90 of about 67,524,308 (281)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
LEGO® Serious Play® (LSP) was used to understand the ideals of connectivity and inclusivity among students, adult learners, and workers in a higher education community.
Cecilia Medupin +2 more
doaj +1 more source
Formality and Friendship: Research Ethics Review and Participatory Action Research
While Participatory Action Research (PAR) is gaining a foothold in geographical research practice, universities and major funding bodies are imposing ethics review procedures that are inherently contradictory to doing PAR.
Megan K. Blake
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
RELATIONS OF VARIOUS SOCIAL ACTORS WITH MARINE DEBRIS IN THE MUNICIPALITY OF CANANEIA, SP [PDF]
This research set out to conduct a participatory diagnosis in the municipality of Cananeia, south coast of Sao Paulo - Brazil, of how different groups of adults with direct links to the marine environment (recyclable waste pickers, fishermen, teachers ...
Daiana Proença Bezerra +1 more
doaj +4 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Review: Ernest T. Stringer (2007). Action Research
STRINGER's book on action research provides an accessible introduction to conducting participatory inquiries for social change. This general overview of the theoretical foundations of action research and methodological challenges is enriched by practical
Tobias Denskus
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Reflections for postgraduate students on writing an action research thesis
The prospect of conducting action research as part of formal academic study can seem quite daunting for many. The academy, often dominated by a positivist approach, does not always appreciate the value and quality of research that is qualitative, action ...
Smith, Steve Wayne
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