Results 181 to 190 of about 647,785 (290)

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

The development of gender- and sex-diverse standardized patients for interprofessional learning: a community-based participatory approach. [PDF]

BMC Med Educ
Siegel JR, Silverstein S, Florescu N, Klevan JR, Sullivan F, Van Der Kloot H, Bass SB, Garfield JL.   +7 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Community Participatory Approach to Design, Test, and Implement Interventions That Reduce Risk of Bat-Borne Disease Spillover: A Case Study from Cambodia. [PDF]

Trop Med Infect Dis
Sok D, Vong S, Lorn S, Srey C, Kenyon M, Ghersi BM, Burgess TL, Griffiths M, Ali D, Faustman EM, Gold E, Gass JD, Nutter FB, Amuguni JH, Peterson J.   +14 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Correction: Development of a comprehensive school anti-bullying logic model in Abu Dhabi: a multi-method participatory approach. [PDF]

Front Public Health
Al-Ketbi A.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Development of a comprehensive school anti-bullying logic model in Abu Dhabi: a multi-method participatory approach. [PDF]

Front Public Health
Al-Ketbi A.
europepmc   +1 more source

Chapter Pitfalls of Participatory Approaches

, 2019
Over recent decades, “participation” has become one of the leading mottos of reform-oriented movements in such diverse fields as democracy, technology, finance, management, mass media, culture, social research methodology and, last but not least, social work. Before our eyes the “change of function” (in the terminology of Karl Mannheim) has taken place:
openaire   +1 more source