Results 141 to 150 of about 209,579 (354)

Democratic Development and the Role of Citizenship Education in Sub-Saharan African with a Case Focus on Zambia [PDF]

open access: yes, 2005
In addressing issues related to problems of democratisation in Africa, this paper attempts to relate the issue to the need for citizenship education and the role that can play in social development.
Abdi, Ali A., Ellis, Lee, Shizha, Edward
core   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

open access: yesAdvanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge   +21 more
wiley   +1 more source

O ORÇAMENTO PARTICIPATIVO E O PAPEL DO ESTADO – THE PARTICIPATORY BUDGET AND THE ROLE OF THE STATE

open access: yesRevista da Seção Judiciária do Rio de Janeiro, 2010
O retorno da democracia direta é objeto do debate político mundial. A repulsa da população pela política e pelas atuais formas de democracia representativa traz a reflexão sobre novas formas de participaç ...
Gabriela Soares Balestero
doaj  

Who is willing to deliberate, and how? Dissatisfied democrats, stealth democrats and populists in the UK: SEI Working Paper 131 [PDF]

open access: yes, 2012
This article draws on a new survey of British citizens to test the hypothesis that there are two quite distinctive types of attitude prevalent among those who are ‘disaffected’ with politics, the ‘dissatisfied democratic’ and ‘stealth democratic ...
Webb, Paul
core   +1 more source

Robotic Materials With Bioinspired Microstructures for High Sensitivity and Fast Actuation

open access: yesAdvanced Science, EarlyView.
In the review paper, design rationale and approaches for bioinspired sensors and actuators in robotics applications are presented. These bioinspired microstructure strategies implemented in both can improve the performance in several ways. Also, recent ideas and innovations that embed robotic materials with logic and computation with it are part of the
Sakshi Sakshi   +4 more
wiley   +1 more source

The utilisation of online alternative media and its implications towards participatory democracy: A Malaysian case / Azlina Kamaruddin [PDF]

open access: yes, 2016
This study examines the utilisation of online alternative media and its implications towards participatory democracy. Since the enactment of the Communication and Multimedia Act 1999, online alternative media such as Malaysiakini, Malaysia Today, and the
Kamaruddin, Azlina
core  

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

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