Results 181 to 190 of about 551,295 (306)

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Participatory design of built environment strategies to enhance movement, wellbeing, and quality of life among incarcerated men. [PDF]

Int J Behav Nutr Phys Act
Giné-Garriga M, Palma C, Signo S, Isanta C, Romeva R, Portillo SA, King AC, Cortés MA, Ballester D, Sebastiani EM.   +9 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Cultural Feasibility of Conversational Robots for Dementia Care in India: Participatory Design Study. [PDF]

J Particip Med
Lima MR, Srinivasan N, Daniels S, Vaitheswaran S, Vaidyanathan R.   +4 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

From participatory design to clinical routine: new concepts for visualizing patient-reported outcomes in breast cancer care. [PDF]

J Patient Rep Outcomes
Doppelbauer L, Karsten MM, Tatzber A, Hatzler L, Gebert P, Brands J, Andriessen R, Pross T.   +7 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Exploring conditions for implementing daily monitoring of Behavioral and Psychological Symptoms of Dementia (BPSD) in dementia care: insights from a participatory design study. [PDF]

BMC Geriatr
Malm J, Odzakovic E, Kåreholt I, Fristedt S, Bielsten T.   +4 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Who participates in 'participatory design' of WASH infrastructure: A mixed-methods process evaluation. [PDF]

PLOS Glob Public Health
Mink TL, Salinger AP, Francis N, Batagol B, Burge K, Ilhamsyah N, Malumu L, Marzaman L, Prescott MF, Putri NI, Sinharoy SS.   +10 more
europepmc   +1 more source