Results 71 to 80 of about 279,255 (349)
Environmental governance: Participatory, multi-level - and effective? [PDF]
Current international and European Union environmental policies increasingly promote collaborative and participatory decision-making on appropriate and multiple governance levels as a means to attain more sustainable policies and a more effective and ...
Fritsch, Oliver, Newig, Jens
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The deliberative turn in participation: the problem of inclusion and deliberative opportunities in participatory budgeting [PDF]
Participation has undergone a communicative shift, which has favoured the organization of new participatory processes based on classic principles of deliberation theory.
Francés, Francisco +1 more
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The purpose of this study to examine the impact of the implementation of Good University Governance Principles on managerial performance in the practice of participatory-based budget management.
Amilin Amilin
doaj +1 more source
Irrigation and water policies in the Mekong region: current discourses and practices [PDF]
Water resource management / Water policy / Water law / Participatory management / Irrigation management / River basins / Governance / South East Asia / Thailand / Cambodia / Laos / Vietnam / Myanmar / China / Mekong ...
Molle, Francois
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Implementing integrated river basin management: lessons from the Red River Basin, Vietnam [PDF]
River basin management / Water resource management / Legal aspects / Water law / Water policy / Institutional reform / Organizational change / Institutions / Governance / Development projects / Participatory management / Vietnam / Red River Basin / Cau ...
Hoanh, Chu Thai, Molle, Francois
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

