Results 51 to 60 of about 75,299 (265)

Participatory Action Research Using Visual Methods

, 2020
Participatory action research (PAR) is a method of investigation which merges theory with action and participation while challenging institutionalized methods of collecting and curating knowledge. It relies on the accumulation of knowledge through participant action and seeks to advance the interests of underrepresented groups and classes.
openaire   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Critical Participatory Co-Analysis: Advancing Analytic Methods for Participatory Qualitative Research

International Journal of Qualitative Methods
New types of transgressive qualitative research can embrace more collaborative forms of truth-sharing and meaning-making, leading to more multivocal insights to advance shared knowledge-building and development goals in broader-reaching ways.
Day Greenberg
doaj   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Assessment of the vulnerability of coastal agriculture to seawater intrusion using remote sensing, GIS, and Multi-Criteria Decision Analysis

International Journal of Digital Earth
The Philippines heavily relies on crop production, with a significant portion cultivated in coastal agricultural areas. However, these farmlands are impacted by salinity intrusion, which adversely affects agricultural productivity.
Nerissa Gatdula, Ariel Blanco
doaj   +1 more source

Sustainable Agroforestry Landscape Management: Changing the Game

Land, 2020
Location-specific forms of agroforestry management can reduce problems in the forest–water–people nexus, by balancing upstream and downstream interests, but social and ecological finetuning is needed.
Meine van Noordwijk, Erika Speelman, Gert Jan Hofstede, Ai Farida, Ali Yansyah Abdurrahim, Andrew Miccolis, Arief Lukman Hakim, Charles Nduhiu Wamucii, Elisabeth Lagneaux, Federico Andreotti, George Kimbowa, Gildas Geraud Comlan Assogba, Lisa Best, Lisa Tanika, Margaret Githinji, Paulina Rosero, Rika Ratna Sari, Usha Satnarain, Soeryo Adiwibowo, Arend Ligtenberg, Catherine Muthuri, Marielos Peña-Claros, Edi Purwanto, Pieter van Oel, Danaë Rozendaal, Didik Suprayogo, Adriaan J. Teuling   +26 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source