Results 121 to 130 of about 776,492 (301)

STREAM Journal, Vol. 1, No. 4, pp 1-16. October-December 2002 [PDF]

open access: yes, 2002
CONTENTS: Hon Mun MPA Pilot Project on community-based natural resources management, by Nguyen Thi Hai Yen and Bernard Adrien. An experience with participatory research in Tam Giang Lagoon, Thua Thien-Hue, by Ton That Chat.

core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

General practitioners’ adoption of generative artificial intelligence in clinical practice in the UK: An updated online survey

open access: yesDigital Health
Background Following the launch of ChatGPT in November 2022, interest in large language model-powered chatbots has soared with increasing focus on the clinical potential of these tools.
Charlotte Blease   +10 more
doaj   +1 more source

Using Participatory Research Methods in Economic Research [PDF]

open access: yes
Research Methods/ Statistical Methods,
MacDonald, Darla Hatton, Weber, Marian
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

IDENTIFYING APPROPRIATE GERMPLASM FOR PARTICIPATORY BREEDING: AN EXAMPLE FROM THE CENTRAL VALLEYS OF OAXACA, MEXICO [PDF]

open access: yes
Identifying the appropriate germplasm to be improved is a key component of any participatory breeding effort because of its implications for impacts on social welfare and genetic diversity. This paper describes a method developed to select a subset of 17
Aguirre, Alfonso   +6 more
core   +1 more source

Using participatory, observational and ‘Rapid Appraisal’ methods: researching health and illness [PDF]

open access: yes, 2010
This chapter reports on the experiences and lessons learned through the use of participatory, locality-based data generation methods to research the intersections between long-term illhealth and poverty among four different ethnic 'communities'
Chowbey, Punita   +2 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Assessing the impact of participatory research in rice breeding on poor rice farming households with emphasis on women farmers: a case study in eastern Uttar Pradesh, India [PDF]

open access: yes, 2016
For the past years since the Consultative Group of International Agricultural Research (CGIAR) Systemwide Initiative on Participatory Research and Gender Analysis (PRGA) was initiated, guides for impact assessment of PRGA have been developed (Lilja and
Atlin, Gary   +4 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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