Results 111 to 120 of about 776,492 (301)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Organization ecosystem for inclusive development in Indonesia: a bibliometric analysis and literature review

Cogent Social Sciences
This study aims to identify, review, and study trends in scientific publications on organizational ecosystems for inclusive development in Indonesia. This study examines how organizations can address issues of diversity, equity, and inclusion (DEI), in ...
Heru Nurasa, Abdillah Abdillah, Qinthara Mubarak Adikancana, Ida Widianingsih   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Analysis of Participatory Research Projects in the International Maize and Wheat Improvement Center [PDF]

Through a survey of scientists from the International Maize and Wheat Improvement Center (CIMMYT) in 2004, this study assessed the extent to which participatory methods had been used by the center, how they were perceived by the scientists, and how ...
Bellon, Mauricio R., Lilja, Nina K.
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

UTILITATEA ŞI RELEVANŢA CERCETĂRII PARTICIPATIVE ÎN INVESTIGAREA FENOMENELOR SOCIALE

Studia Universitatis Moldaviae: Stiinte Sociale, 2017
În acest articol este luată în vizor o nouă paradigmă de cercetare a fenomenelor sociale, care pune accentul pe abor­darea participativă: actorii sociali studiaţi devin membri ai echipelor de cercetare, favorizând cunoaşterea din interior şi aprofundată ...
Anastasia OCERETNÎI
doaj  

Organizing Facilitated Poster Discussion Sessions: Their Inspiration, Planning, and Implementation at the C*Sci2023 Conference

Citizen Science: Theory and Practice
The C*Sci 2023 conference, held by the Association for the Advancement of Participatory Sciences (AAPS; until 2024 known as the Citizen Science Association) in Tempe, Arizona in May 2023, aimed to bring those involved in participatory science together in
Sara Duncan, Alison Cawood, Julie Tuttle, Reanna Putnam   +3 more
doaj   +1 more source

African primary care research: Participatory action research

African Journal of Primary Health Care & Family Medicine, 2014
This article is part of the series on African primary care research and focuses on participatory action research. The article gives an overview of the emancipatory-critical research paradigm, the key characteristics and different types of participatory action research.
openaire   +6 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Inclusive resilience in Indonesia: case of disability anticipation within inclusive development

Discover Social Science and Health
This study investigates the dynamics of social resilience and inclusive development for individuals with disabilities in Indonesia, addressing significant challenges such as urbanization, poverty, and inequality.
Abdillah Abdillah, Ida Widianingsih, Rd Ahmad Buchari, Heru Nurasa   +3 more
doaj   +1 more source