Results 171 to 180 of about 765,758 (302)

Methodologies of Care: A Multimodal, Participatory Research Approach with Vulnerable Families Among South African Communities. [PDF]

Methods Protoc
Reid J, Johannes C, Wareley S, Ngadhi C, Nginase A, Demetriou K, Roman NV.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A community-based participatory research program to identify lead exposure risks and community priorities. [PDF]

Discov Soc Sci Health
Zavala-Garcia J, Ali N, Arango O, Brady C, Esquivel-Cote R, Goldsmith ST, Link H, Lugo D, Matos S, McDermott-Levy R, Shakya KM, Smith DJ, CCATE Círculo de Salud .   +12 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Understanding the mental health of adolescents and young adults in rural South Africa through participatory research. [PDF]

PLOS Glob Public Health
Mthiyane N, Zikhali M, Xulu S, Ngwenya N, Sherr L, Hunt X, Seeley J, Copas A, Harling G, Shahmanesh M, Zuma T.   +10 more
europepmc   +1 more source

Participatory Evaluation of Participatory Research

Participatory Evaluation of Participatory Research
この講演では、1)研究・開発事業における評価という役割の変化、2)事業評価における参加型アプローチという新しい手法の誕生と3)参加型研究の評価という新たな分野への朝鮮とその課題について述べる。キーとなる重要な概念と実践方法を理解していただくために、アジアで実際に行われた農業研究と開発関連の実例を使いながら話をすすめていきたい。研究・開発事業では、評価は、説明責任と透明さを確実なものとするためのただ単なる手段として今までみなされていた。評価は事業がその目的を達成したか、資源を有効に使うことができたかどうかを図るためによく使われるが、これは公の場において公正さの審査を受けるためである。ほとんどの評価事業はプロジェクトの提案者、実施者とドナーのニーズにこたえるように組み立てられている。評価は、私意のない ...
openaire  

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Using Community-Based Participatory Research Strategies to Promote Liver Cancer Prevention. [PDF]

Soc Sci
Zhu L, Lu W, Yeh MC, Ma GX, González ET, Traub K, Fraser MA, Rubio-Torio N, Wong A, Tan Y.   +9 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source