Results 71 to 80 of about 765,758 (302)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Research in Partnership With Older People—Involvement in Conducting and Analysing Focus Groups

Health Expectations
Introduction Data collection and analysis in collaboration with co‐researchers has rarely been described, and its impact on the research process and outcomes remains unknown.
Nadja Reeck, Anna Völkel, Margarethe Mammes, Dagmar Urbahn‐Schiefer, Bettina Reineking, Tim Stuckenschneider, Anna Levke Brütt   +6 more
doaj   +1 more source

“The more you learn, the more you can influence”—learning circles to support citizen science in Parkinson's disease: a pilot study in Sweden

Frontiers in Public Health
IntroductionParkinson's disease (PD) is the fastest growing neurological condition, making it a public health concern. There is still much to be learned about this complex disease, and citizen science–the involvement of the public in scientific research ...
Jamie Linnea Luckhaus, Therese Scott Duncan, Carina Hellqvist, Carina Hellqvist, Sara Riggare   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

PRGA program publications list [PDF]

, 2016
List of PRGA ...
CGIAR Systemwide Program on Participatory Research and Gender Analysis for Technology Development and Institutional Innovation
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The role of music and singing as research methods to improve migrants’ involvement in health research and policy-making

Health Research Policy and Systems
This commentary explores the potential of arts-based research methods, particularly music and singing, to address issues of participatory inequity and the structural bias this creates in health research systems and policies.
Helen Phelan, Ahmed Hassan, Anne MacFarlane   +2 more
doaj   +1 more source

Making patient experience actionable: applying importance-performance analysis to guide improvements in Swedish healthcare

Frontiers in Health Services
IntroductionUnderstanding how well healthcare systems meet what patients value is central to person-centered care. As a first objective of this study, the alignment between what Swedish patients consider important in healthcare and what they experience ...
Therese Scott Duncan, Louise Lind, Louise Lind, Li Åslund, Li Åslund, Eva Dieker, Sara Riggare   +6 more
doaj   +1 more source

Using Participatory Research Methods in Economic Research [PDF]

Research Methods/ Statistical Methods,
MacDonald, Darla Hatton, Weber, Marian
core   +1 more source