Results 71 to 80 of about 232,558 (307)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The role of music and singing as research methods to improve migrants’ involvement in health research and policy-making

Health Research Policy and Systems
This commentary explores the potential of arts-based research methods, particularly music and singing, to address issues of participatory inequity and the structural bias this creates in health research systems and policies.
Helen Phelan, Ahmed Hassan, Anne MacFarlane   +2 more
doaj   +1 more source

PARTICIPATORY RESEARCH IN THE MANAGEMENT OF TERRITORIAL DEVELOPMENT. INVESTIGATIONS IN LIVEZILE-RIMETEA MICRO-REGION (2001-2002 and 2007-2008) [PDF]

The aim of this study is to present some important aspects of the way inwhich participatory research may contribute to the management of territorialdevelopment, through the identification of problems and development opportunities in agiven territory.
Mihai Pascaru
core  

Mapping the Trend of Humor Studies in Educational Arena: A Text-analytic Approach

, 2022
Humor is considered an educational method that can be implemented in educational processes with a wide range of educational variables. Examining the scope of research on educational humor has the potential to guide future studies.
Fatih ERDOĞDU
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Making patient experience actionable: applying importance-performance analysis to guide improvements in Swedish healthcare

Frontiers in Health Services
IntroductionUnderstanding how well healthcare systems meet what patients value is central to person-centered care. As a first objective of this study, the alignment between what Swedish patients consider important in healthcare and what they experience ...
Therese Scott Duncan, Louise Lind, Louise Lind, Li Åslund, Li Åslund, Eva Dieker, Sara Riggare   +6 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Harnessing public perception of cheetah reintroduction in India to facilitate management through participatory decision-making

Scientific Reports
Scientists, conservationists, and decision-makers are debating the restoration of the cheetah population in India, aiming to protect biodiversity and habitats, while several experts express concerns and question the benefits and drawbacks of the ...
Debaleena Chatterjee, Bhupendra Singh Adhikari, Tanoy Mukherjee   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Exploring Community-based Research Values and Principles: Lessons Learned from a Delphi Study

Gateways, 2018
Community-based research (CBR) is a relatively new methodology characterised by the co-generation of knowledge. As CBR is integrated into institutional frameworks, it becomes increasingly important to understand what differentiates CBR from other ...
Jenny Francis, Miu-Chung Yan, Hartej Gill   +2 more
doaj   +1 more source