Results 81 to 90 of about 512,842 (292)

General scaling laws of space charge effects in field emission

open access: yesNew Journal of Physics, 2021
The characteristics of field electron and ion emission change when the space charge formed by the emitted charge is sufficient to suppress the extracting electric field. This phenomenon is well described for planar emitting diodes by the one dimensional (
A Kyritsakis, M Veske, F Djurabekova
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Numerical Simulation of Spacecraft Charging Attributed to Ionospheric Plasma in Polar and Equatorial Environment

open access: yesIndonesian Journal of Geography, 2020
The presence of spacecraft in ionospheric plasma can change plasma properties, vice versa plasma can lead to charge buildup on spacecraft. The level of charging, through electric potential of spacecraft, initially depends on plasma density.
Nizam Ahmad, Hideyuki Usui
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Lambda Polarization in an Exact Rotating and Expanding fluid dynamical model for peripheral heavy ion reactions

open access: yes, 2015
We calculate the Lambda polarization in an exact analytical, rotating model based on parameters extracted from a high resolution (3+1)D Particle-in-Cell Relativistic hydrodynamics calculation.
Csernai, Laszlo P.   +2 more
core   +1 more source

Particle-in-Cell Simulations of Quantum Plasmas

open access: yes
Room-temperature metals and semi-metals which consist of a gas of bound electrons in a near-continuum band structure can be classified as cold quantum plasmas. This insight suggests that Particle-in-Cell (PIC) simulations, traditionally used for modeling classical plasmas, may be adapted for the next generation of nanoscopic simulations in photonics ...
Ngirmang, Gregory K.   +4 more
openaire   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Corrigendum: Performance simulation of a 5 kW hall thruster

open access: yesFrontiers in Materials, 2023
L. Yang, P. Y. Wang, T. Wang
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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