Results 91 to 100 of about 3,646,993 (304)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Глаголи с елемента “си” / “sobie” в българския и в полския език

open access: yesZeszyty Cyrylo-Metodiańskie, 2017
Verbs with the Element „си” / „sobie” in Bulgarian and Polish Languages: The paper examines the phenomenon of reflexive personal pronouns for the dative case, used with verbs in several Slavic languages.
Savova, Dimka
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Focus Particles (Just, Even, And, etc.) in the Advertisements

open access: yesRespectus Philologicus, 2015
The article has been prepared by carrying out the analysis of focus particles: just, even, and, etc. It is important to note that particles play a very important role in linguistic pragmatics: they convey additional meanings called the conventional ...
Danguolė Valančė
doaj   +1 more source

Particle identification

open access: yes, 2011
Particle IDentification (PID) is fundamental to particle physics experiments. This paper reviews PID strategies and methods used by the large LHC experiments, which provide outstanding examples of the state-of-the-art.
Lippmann, Christian
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Computational analysis of shock-induced flow through stationary particle clouds

open access: yes, 2019
We investigate the shock-induced flow through random particle arrays using particle-resolved Large Eddy Simulations for different incident shock wave Mach numbers, particle volume fractions and particle sizes.
Omang, Marianne Gjestvold   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Functioning of the word combination “da vsio ravno” in modern Russian language

open access: yesStudia Humanitatis
The article examines the use of the word combination “da vsio ravno” by modern native speakers of Russian using examples from the Russian National Corpus. This combination includes the polyfunctional word “da”, which can act as an adversative conjunction
Krylova Maria Nikolaevna
doaj  

Tribology in Natural Sand Dust Environment

open access: yesTribology Online, 2008
The tribological problem in natural sand dust environment was proposed and an equipment for simulating the natural sand dust environment based on Multi-Venturi structure was introduced for studying the tribological problem.
Dongfeng Diao, Tonghai Wu
doaj   +1 more source

Home - About - Disclaimer - Privacy