Results 111 to 120 of about 4,687,120 (358)
Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig +10 morewiley +1 more sourceMultiresolution particle filters in image processing [PDF]
, 2006 Recursively estimating the likelihood of a set of parameters, given a series of observations, is a common problem in signal processing. The particle filter is now a well-known alternative to the Kalman filter.Mullins, Andrew, Wilson, Roland, Rajpoot, Nasir M., Bowen, Adam +3 morecore Charged-particle multiplicities in pp interactions at measured with the ATLAS detector at the LHC [PDF]
, 2010 The first measurements from proton–proton collisions recorded with the ATLAS detector at the LHC are presented. Data were collected in December 2009 using a minimum-bias trigger during collisions at a centre-of-mass energy of 900 GeV.D Muenstermann, A Marzin, Alessandria, F, Buis, E.J., Arce ATH, Eppig, A, Smizanska, M, Blair, R, V Bansal, Strang, M, Ask S., Hasegawa, S., M. Caprio, L Dell'Asta, Carminati, L., Aguilar-Saavedra, J. A., J Deng, Cantero, J., Hubaut, F., Meyer, C., Harper, R, M De Oliveira Branco, Y Doi, Dudarev, A., Oren, Y., B Budick, Borissov, G., Golovnia, S, K Dindar Yagci, Hellman, S, Harper, D, F Corriveau, Korn, A., Laplace, S., Magalhaes Martins, P, Higón Rodríguez, Emilio, Catmore, J.R., Kim, H., D. Chakraborty, Cavalli Sforza, M, Kanzaki, J, C. Booth, Kopikov, S, Marchand, J.F., Stockmanns, T., C Borer, C Mora Herrera, Norton, PR, Epp, B., Fernando, W, Ahlen, S. P., Froeschl, R., Richter, D., J. Cammin, Sas, L, Flammer, J, Brooijmans G., Poffenberger, P., Leney, K, M Corradi, M Gosselink, Dameri, M., Butler J. M., R M Buckingham, Abreu, H, Pizio, C., Rossi, L., Rud, V.I., Jon-And, K., B. Caron, L Capasso, Wendler, S, G Negri, Magalhaes Martins, PJ, Peeters, S.J.M., Köneke, K., Tasevsky, M., Acharya B. S., Cervetto M., E Dawe, Siragusa, G, I Jen-La Plante, W Lavrijsen, Rulikowska-Zarebska, E, Salzburger, A., Panes, B, Rossi, LP, Arms, K.E., Hadley, DR, Vacek, V, Carlino, G., Binder M, J Blocki, Torrence, E., Branco, MD, Oliveira, M, Tskhadadze, E.G., Thompson, R.J., Bogaerts, J, Snyder, S, Kirk, J, Ziolkowski, M, Jelen, K., Korotkov, VA, C Collins-Tooth, Kourkoumelis, C., Carron Montero, S, Brochu, F.M., Dai, T., Lefebvre, M, Lilley, J, Bernat, P., G. Alexandre, Salto Bauza, O., Wickens, F.J., K A Johns, Montero, SC, I. N. Aleksandrov, A Andreazza, Engl, A, Asai S, Arnault, C., Siebel, M, Snuverink, J., Lebedev, A.,, Kiryunin, A, Sijacki, DJ, Anh, TV, Abat E., M. Aliyev, Asai M, Genest, MH, Werthenbach, U, Benedict, B, Thioye, M, Siebel, A, Vuaridel, B, Negri, G., Valkar, S, van Der Kraaij, E., Olszewski, A., Wappler, F., Knue, A, D. Buira Clark, D Froidevaux, Harris, O, Hughes, G., Szczygiel, R.R., O G Grebenyuk, C Lapoire, Cheatham, S, Joram, C, Mashimo, T, M. Cervetto, Gupta, A., Smizanska, M., Gilbert, L, Hughes, EW, Montoya, G. D. Carrillo, Dosil, M, V A Gapienko, Padilla Aranda, C., Bright-Thomas, P. G., Kersten, S, P. Booth, S Hillert, V. F. Chepurnov, Weng, Z., Jha, M.K., Maxfield, S.J., M C Conidi, Schaepe, S., Schovancova, J., Reale, V, Beck, G. A., Sircar, A., Vassilakopoulos, V, Bruneliere, R, Darlea, G, C Meroni, D Goldin, Pimenta dos Santos, M.A., P A Bruckman de Renstrom, Massol, N, M G Alviggi, M Aharrouche, Benoit M, Morello, G., Negri, A., Canelli F., Kawamoto, T, Castaneda Miranda, E, Kim, PC, J A Frost, Schamberger, RD, Haboubi, G, O. Blanch, K Augsten, A Cerri, Ji, W., Michal, S, P Giusti, Lombardo, VP, J Fuster, D. G. Charlton, U Blumenschein, Salihagic, D, Mohrdieck-Möck, S., Karnevskiy, M., B. Budick, Y Azuma, Liu, C., Boldyrev, A., González de la Hoz, Santiago, Ertel, E., Batley, J.R., Cornelissen, T, Schwierz, R., H Abramowicz, Nauyock, F, Kim, SH, A G Goussiou, Asner, D., Fedin, OL, Barr, A, Arguin, JF, Köpke, L., Ishikawa, A, Nisati, A, Strong, J, Deviveiros, P, Marx, M, Liu, D., Barreiro Guimarães da Costa J, Burckhart H., Hendriks, P.J., Schlereth, JL, V. Andrei, Orr, R, Carrillo Montoya GD, Lellouch, D., G. Cataldi, Bini, C, Hedberg, V, Zdrazil, M, Ferretti, C., Kobel, M, Bednyakov, V, Eppig, A., S P Ahlen, Orsini, F., Lubatti, H, CAMARRI, PAOLO, D Fasching, Puzo, P, Yu, J, B Lundberg, Lancon, E, Marroquim, F, Yu, D, Muir, A., Abdelalim, A. A., Liss, T, Lambacher, M., Åkesson, P. F., Ellis, N, Benslama, K., Ellis, K, Kolanoski, H., J Klaiber-Lodewigs, Oakham, F.G., P Ferrari, Baak, M, Muino, P, Bates, RL, Kowalewski, R., Sjölin, J., F Filthaut, Oreglia, M, Parzefall, U, Hillier, S, Woehrling, E, Samset, BH, P Bernat, Woudstra, MJ, Charlton, David; id_orcid, Huseynov, N, Bellina, F, Watson, A.T., N. Benekos, Medinnis, M., Charlton, D. G., R. Bates, Sadrozinski, H, Huang, GS, D Lacour, Arnault C., Tamsett, MC, T J McMahon, Zhou, Y., Buchholz R., Bauza, OS, Pauly, T, V. Chiarella, R Febbraro, J. Alonso, J-F Grivaz, Lellouch, J., A Lebedev, Errede, S., Liu, H., B C LeGeyt, Valderanis, C, Kabachenko, VV, Jorgensen, S., Petrucci, F., Rijssenbeek, M., Kaci, M, Tuts, P.M., Marchese, F., De Salvoa, A, J Idarraga, Krumshteyn, Z, Patwa, A, Dwuznik, M., Shatalov, PB, Smirnova, O, Arguin, J-F., Doi, Y., Cooke, M., Strong, J.A., Richter, R., Smirnova, L, Diehl, E, M He, Oberlack, H, R Hackenburg, Ottewell, B, D Oliveira Damazio, Castaneda Hernadez, A.M., Kim, MS, Mangin-Brinet, M, Avolio, G, Beau T., Castillo Gimenez, V., Nikolic-Audit, I, O Biebel, Traynor, D, Weng, Z, Vitale, A., A Lister, A Gorišek, A G Kholodenko, Milov, A, Haller, J, M Nash, Donadelli, M., X Ju, Grillo, A.A., Morales, MIP, Izen, J.M., R Cherkaoui El Moursli, Blair, RE, Obermaier, M., A P Colijn, Donadelli, M, R Moles-Valls, Ros, E., Martynenko, V., I M Gregor, B Li, Argyropoulos, T, Ciocca, C., Blanch, O, G. Bobbink, Grimaldi, F., Lipeles, E., R. Bartoldus, Morin, J, M Morii, Bhimji W, Acharya, B.S., Epp, B, Drohan, J.G., Rybar, M, Buis EJ, Zobernig, G., A Hoecker, Kroha, H, Coccaro, A., S Hou, Gössling, C., Beare, B, G. A. Beck, Morozov, S, Tsiareshka, PV, Clark PJ, Meroni, C, Tayalati, Y, Ciftci AK, Andrieux, M.-L., Branchini P, Y. Bai, Lie, K, Davygora, Y., Kawamura, G, Braun, H.M., X Li, Cardarelli R., H Garitaonandia, Alonso J., V Grabski, S. Bentvelsen, Davies, M, Pommès, K., Gnanvo, K, Grimm, K., Nesterov, S.Y., Andeen T, Strang, M., S N Golovnia, Klemetti, M, Lozano, M, Blumenschein U, Keung, J., Lantzsch, K., Sbrizzi, A., M Idzik, Villani, EG, Kostka, P., Broggi E., T Naumann, Bartko H., Fournier, D., O'Neil, D.C., Davidson, D.W., T. J. Brodbeck, T Nyman, Montarou, G., Mima, S., Straessner, A., Fiorini, L., Tylmad, M., Brunckob, D., Potter, C.T., Dudarev, A, Busato E, Schroeder, C., Chesneanu D., Oliver, C, L. Batkova, W. Bell, Dauvergne, J, Oliver, J, L Di Ciaccio, Lange, C, J M Maugain, Chafaq, A., Lantzsch, K, A Oyarzun, Grivaz, J.-F., J L Lane, E V Bouhova-Thacker, F Garberson, Francavilla, P., Battistin M, Gorini, B., Wiglesworth, C., W K Brooks, Bromberg C., Ueda, I., M Ellert, Beddall, A, Hernandez Jiménez, Y., Kroha, H., Tsiskaridze, V, Ren, Z.L., Alhroob, M., van Eldik, N., J Ludwig, Fisher, S, Bell, William, Kurata, M, Ren, Z, P. Calfayan, Maettig, S, Lane, JL, Aliev M., Vandoni, G., Fisher, M, Badescua E, Lobodzinska, E., Lifshitz, R., CHIEFARI, GIOVANNI, Stiller, W., Bartoldus, R., Maettig, F, Bagnaia P, Lagouri, T, Maettig, P, del Papa, C., Patricelli, S., Verducci, M., Felzmann, CU, Goussiou, AG, C. Benchouk, P. A. Bruckman, Odaka, S, Levonian, S., Wielers, M., Kononov, AI, Nikolic-Audit, I., G Ionescu, C Lange, Crupi, R, Puigdengoles, C., M Marcisovsky, Mudrinic, M., de Jong, P., Goldin, D, Mccarn, A., O Kortner, Sun, X.H., Lecompte, T., Baranov, S, Mechnich, J., J. R. Carter, S Kotov, Cheong, ALF, Hori, T., M King, Soukharev, A, Baranov S. P., U De Sanctis, Ciftci, R., Oliver Garcia, E., K Facius, X. S. Anduaga, Zsenei, A., Strube, J., Hajduk, Z, Urkovsky, E., Idzik, M, Zhou, B., Schwemling, Ph., Alexandre, G, Walsh, S, J Ferencei, Aleksandrov IN, Tovey, DR, Burgess, T., Kado, M., Khubua, J., M Nožička, Dannheim, D., Spagnolo, S., A Knue, Ikeno, M., M. Ciubancan, Gagnon, P., Mete, A.S., Klok, P, Duerdoth, I.P., Bachy, G, Nakahama, Y., A Guida, de Lotto, B., P. J. Clark, Rybar, M., Schumm, BA, G Crosetti, M Delmastro, S Haider, Aharrouche, M, G. Alexander, B Mansoulie, Bremer, J., Cowan, G, Gadfort, T, Ozone, K., Ekelof, T., Peak, L.S., Shupe, M, del Prete, T., Aderholz, M., M Barisonzi, Kluth, S., Chen X., Cakir O., Errede, D., Sipica, V., S Gadomski, El Moursli, RC, Steele, G., M Ahsan, Black, K.M., A J Armbruster, Calafiura P., Seidel, SC, Cattai, A., Knobloch, J, Biesiada J., Nugent, I.M., Hryn'ova, T, G Boorman, M Bruschi, Sartisohn, G., Brandt G., Archambault, JP, D Costanzo, Ladygin, E., Kopikov, S.V., Rubinskiy, I., Fratina, S., Bertinelli F, D Goujdami, Makovec, N, Lundberg, B, Kabana, S., L. A. Bella, J. Buchanan, Giordani, M.P., Lundberg, J, Bruschi, M, S. Allwood Spiers, A. M. Castaneda, Manjavidze, ID, Sauvage, G, Giorgi, F, Bazalova M, Bednyakov, V. A., Gorini, E., Martin Dit Latour, B., Zhou, N., Poveda, J., Grosse-Knetter, J., Ohshita, H, Frank, T, M Barbero, Azuelos, G, Cerutti, F, Arms, K, D Chakraborty, Konovalov, SP, Petrolo, E., Cheplakov A., N Grigalashvili, Bouhova-Thacker EV, Abat, E., Weber, M.D., A Gershon, Calvet, D., Blocker C., St Denis, St, S Hellman, Nanava, G, Nairz, A.M., Slater, M., Curatolo, M., Djobava, T., Landsman, H, N. Amram, Couyoumtzelis, C., Hassani, S, Kisielewski, B, Reichold, A, M Bona, Cavalleri P., Teixeira Dias Castanheira, M., Qin, Z., F Bauer, Hrynʼova, T., Hillert, S, M Cavalli-Sforza, Clemens, J.C., Moisseev, A, Wingerter-Seez, I., Krieger, N, R Kehoe, Rossi, E., Krieger, P, C Melachrinos, Barr, A.J., Dragic, J., Taylor, G., . AAD, K Hanagaki, Childers, J, Sandvoss, S, García García, Carmen, C Omachi, Taylor, FE, Bawa, HS, Keeler, R., Maltezos, S., Brandt A., Chu, M. L., Belotskiy K., Slattery, R, S Franchino, Stelzer-Chilton, O., Simic, L, Lau, Wing, Lys, J., Brelier B, Bachacou H., Imbault, D., Anduaga XS, P Jež, Saleem, M., Dhullipudi, R., Stradling, AR, Kar, D., Tokunaga, K., Moszczynski, A, Goggi, V., Moye, T, V. G. Bondarenko, Athar, B., Laporte, JF, Taylor, C., K. Bos, Kishimoto, T., Subramania, S, Mechtel, M, Bardin, DY, Sivoklokov, S.Yu., Nugent, IM, Lehmacher, M., Bocian D, Kono, T, Schultz-Coulon, HC, Cerrito L., St Denis, R., O Jonsson, Saleem, MS, Benchouk C., C Driouichi, M. Caprini, Bunse M., Juste Rozas, A., M D'Onofrio, Dzahini, D, Buttinger, W., St Denis, RD, Bitenc U, Paramonov, A, Joffe, D, Weidberg, Anthony, P. K. Behera, P de Jong, Gray, H, Donega, M., Gray, J, B J Gallop, M Kocian, Bathe, S., Rosenbaum, G, Rosenbaum, F, Blocker C, Potter, KP, Gillberg, D, M H Genest, N Hill, Banas, E., Hostachy, JY, Tani, K., Martin, TA, Zhu, J., Zaets, V, E Graziani, Esposito, B, Bianchi, R. M., Diglio, Sara, Milov, A., Beau T, Joseph, J., Bacci, C, Malecki, Pa., M. Beretta, Tani, K, Morin, J., H M Gray, Harris, OM, Zhu, H., Ciocca, C, Wu, SL, Einsweiler, K., Haller, J., Kortner, O., D Kharchenko, Cranshaw, J., Venturi, M., Tokunaga, K, Bell W. H., Chepurnov, V. F., Z Liang, Charron, S., M Garcia-Sciveres, S Migas, Reljic, D, Dragic, J, Brandt O., Pérez Garcia-Estan, M.T., S. Bathe, Mechnich, J, Prokoshin, F, Mcfayden, J.A., De Groot, N, V N Gushchin, G Hughes, Åkesson, T.P.A., P. Behera, Ben Ami S, A. Barashkou, Lebel, C, Fernandes, B, M. Aurousseau, G Ordonez, Trinh, TN, Voss, KC, Burckhart, H., Muir, A, Prasad, S., M Elsing, Plamondon, M, Sevior, M.E., Ehrich, T., Royon, C, Vartapetian, A, Buckley, AG, Stockmanns, T, Montero, S, O'Shea, V., Trivedi, A., Uchida, K., Chapman, J.D., S. B. Harpaz, A. M. Castaneda Hernandez, Macek, B., S. Chekulaev, Abdallah J, N Kundu, Labarga, L., Hare, G, Blazek, T., Koutsman, A, Meoni, E., Harkusha, S., Martin, P., Harvey, A., G Eigen, Gallop, BJ, Dube, S., J. Arguin, Knecht, N, R de Asmundis, T Alexopoulos, Royon, C.R., Caloba, L, Green, B., Tassi, E, Cole, B., Kotov, K.Y., Bertin A, Calderini G, A Astbury, Pasqualucci, E., Skvorodnev, N., Roe, S., K Copic, Lessard, J.-R., Fiolhais, MCN, H. Burckhart, M-L Andrieux, Fichet, S, Tikhomirov, V, Fenyuk, A.B., Salvatore, D., Potter, C.J., Garrido, M, Asman B., Vuillermet, R, Turra, R., Oda, S, Schuler, G., Cogan, JG, Randrianarivony, K., G Cataldi, Klimentov, A., K J C Leney, A Mitra, Chen T., Cowden, C, d'Onofrio, M., Brock I., Pagan Griso, S., Del Peso, J, T. P. A. Åkesson, Rosenberg, EI, Le Dortz, O, Strom, D.M., Y. Coadou, Mcpherson, R.A., Booth PSL, Kass, R, R. Ciftci, Protopopescu, S, Darbo, G., Kersevan, BP, Joseph, J, R. Alon, Papadopoulou, Th.D., Castrovillari F, Cobal M, Zhu, CG, L Chen, Antos, J, Rubinskiy, I, Chen S., Kaczmarska, A, W. Brooks, Binder, M., Gorfine, G, Mandelli, L., J Odier, Harper, R., Alexa, C, Anulli F, Osborne, L.S., Salvatore, F., A A Grillo, Barbaro Galtieri, A., Bogaerts, J. A., K Jon-And, Bugge L., Z V Krumshteyn, Kuehn, S., A Canepa, U Kruchonak, G Ciapetti, Kantserov, VA, Kubota, T., Schaile, D., Morettini, P, Nadal, J, Bucci, E, Pedrosa F. Baltasar Dos Santos, Bucci, F, Potter, CJ, Harpaz, S, Stroynowski, R, Romeo, G, R Beccherle, Torregrosa, E, R M Bianchi, Voss, R., Schaffer, AC, Amaral P., P Cwetanski, D'Auria, S, Potter, CT, Hance, M., Ko, B, Mitsui, S., Yurkewicz, A, Makouski, M, G. Alimonti, Teixeira-Dias, P, J. M. Butler, Chelstowska, M.A., Chen H., Blanch, O., Sidhu, J., Sicho, P, D Berge, M Losada, Sicho, R, Teixeira-Dias, R, Niinimaki, Markopekka Juhani, Nyman, T., Bella, L. Aperio, M Johansen, Dauvergne, JP, Chiefari, G, Capriotti D, Booth, P., G Battistoni, S Arfaoui, J Hrivnac, Papadelis, A, E Oliver Garcia, Martin, JP, Buira-Clark, D., Chu, M.L., do Vale, M, G. P. Benincasa, S.w. Banerjee, Bondarenko, VG, Ciapetti G +999 morecore +1 more sourceTranscriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel +14 morewiley +1 more sourceInteraction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen +9 morewiley +1 more source
