Results 121 to 130 of about 4,687,120 (358)
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Intracisternal A Particles and C Particles [PDF]
A J, Dalton, S E, Stewart
openaire +2 more sources
V članku bomo na temelju skladenjskopomenske, besedilotvorne in pragmatskosporočilne preučitve členkov na omenjeno nepregibno vrsto pogledali z zornega kota njihove obveznosti (nefakultativnosti) in neobveznosti (fakultativnosti) v stavku/povedi in dalje
Mojca SMOLEJ
doaj
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Parallelized Particle and Gaussian Sum Particle Filters for Large Scale Freeway Traffic Systems [PDF]
Large scale traffic systems require techniques able to: 1) deal with high amounts of data and heterogenous data coming from different types of sensors, 2) provide robustness in the presence of sparse sensor data, 3) incorporate different models that can ...
Gning, Amadou +7 more
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Particle Code Simulations with Injected Particles [PDF]
As problems we are interested in become more complex, we often find our simulations stretching the limits of available computer resources. For example, an interesting problem is simulation of dissipation processes in sub-critical collisionless shocks.
openaire +1 more source
Particle size analysis is an extremely broad area that covers a wide range of applications and techniques. In past reviews (Al,A2), we have attempted to include as many major techniques as possible that could be of interest to analytical chemists and ...
G. Gee, D. Or
semanticscholar +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Occupational exposure to particles and incidence of stroke
OBJECTIVES: This paper aims to investigate the relation between occupational exposure to particles, particle size, and the incidence of ischemic and hemorrhagic stroke.
Bengt Sjögren +8 more
doaj +1 more source

