Results 141 to 150 of about 4,687,120 (358)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

A particle is not a particle is not a PARTICLE [PDF]

open access: yesJournal of Exposure Science & Environmental Epidemiology, 2002
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Fokusdomäne von Gradpartikeln im Deutschen und Russischen

open access: yesLinguistik Online, 2000
This article deals with the groups of scalar focus particles (grading particles=Gradpartikeln) in German and Russian. The aim is to provide a rough overview of similarities and differences in the syntax of 'sogar/dazhe' groups.
Poljakova, Svetlana
doaj  

Smoothed particle hydrodynamics modelling for failure in metals [PDF]

open access: yes, 2010
It is generally regarded to be a difficult task to model multiple fractures leading to fragmentation in metals subjected to high strain rates using numerical methods.
Strand, Russell K
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Discrete Particle Swarm Optimization for the minimum labelling Steiner tree problem

open access: yes, 2008
Particle Swarm Optimization is an evolutionary method inspired by the social behaviour of individuals inside swarms in nature. Solutions of the problem are modelled as members of the swarm which fly in the solution space.
N. Mladenović   +8 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Stimuli-responsive hydrogel patches for resolving pH with magnetic particle spectrometry (MPS)

open access: yes
Magnetic particle spectrometry (MPS) enables the characterization of magnetic nanoparticles (MNPs) in terms of their nonlinear magnetic behavior, which also depends on the particles’ hydrodynamic mobility and, consequently, on the local environment ...
Bakenecker, Anna   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy