Results 151 to 160 of about 4,687,120 (358)
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
A Study of Particle Trajectories In A Gas Turbine Intake [PDF]
An experimental and theoretical study of the particle trajectories in a gas turbine intake has been presented. computer model was written to simulate a particle behaviour flight in a theoretical flow which was assumed to inviscid ...
Tan, S. C.
core
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Experimental Methods for Model Parameters in the Discrete Element Method
The Discrete Element Method (DEM) is a widely used numerical method for studying, analyzing, and optimizing particulate processes. Based on contact models, DEM can predict the interactions of particles and particles with wall surfaces.
Fabian Krull +2 more
doaj +1 more source
A tutorial on particle filters for online nonlinear/non-Gaussian Bayesian tracking
M. Arulampalam +3 more
semanticscholar +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Solar flare particle acceleration in collapsing magnetic traps
Electronic redacted version excludes material for which permission has not been granted by the rights holderThe topic of this thesis is a detailed investigation of different aspects of the particle acceleration mechanisms operating in Collapsing Magnetic
Grady, Keith J.
core
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source

