Results 161 to 170 of about 4,687,120 (358)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Multiple object tracking using an automatic veriable-dimension particle filter
Object tracking through particle filtering has been widely addressed in recent years. However, most works assume a constant number of objects or utilize an external detector that monitors the entry or exit of objects in the scene.
Salgado Álvarez de Sotomayor, Luis +2 more
core
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
A discrete binary version of the particle swarm algorithm
J. Kennedy, R. Eberhart
semanticscholar +1 more source
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Gopmandal, PP +2 more
core
Modelling of impact on a fuel tank using smoothed particle hydrodynamics [PDF]
This paper describes a modelling approach for the simulation of hypervelocity impact on fuel tanks using the Smoothed Particle Hydrodynamics (SPH) method.
De Vuyst, Tom +3 more
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source

