Results 161 to 170 of about 4,687,120 (358)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Multiple object tracking using an automatic veriable-dimension particle filter

open access: yes, 2010
Object tracking through particle filtering has been widely addressed in recent years. However, most works assume a constant number of objects or utilize an external detector that monitors the entry or exit of objects in the scene.
Salgado Álvarez de Sotomayor, Luis   +2 more
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

A discrete binary version of the particle swarm algorithm

open access: yes1997 IEEE International Conference on Systems, Man, and Cybernetics. Computational Cybernetics and Simulation, 1997
J. Kennedy, R. Eberhart
semanticscholar   +1 more source

Nonlinear effects on migration of charged spherical rigid/soft particle in an unbounded electrolyte solution

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Gopmandal, PP   +2 more
core  

Modelling of impact on a fuel tank using smoothed particle hydrodynamics [PDF]

open access: yes, 2005
This paper describes a modelling approach for the simulation of hypervelocity impact on fuel tanks using the Smoothed Particle Hydrodynamics (SPH) method.
De Vuyst, Tom   +3 more
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Review of particle physics

open access: yes, 2010
Nakamura, K.   +2 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

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