Results 31 to 40 of about 66,207 (176)
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Direct laser acceleration of electrons in free-space [PDF]
, 2015 Compact laser-driven accelerators are versatile and powerful tools of unarguable relevance on societal grounds for the diverse purposes of science, health, security, and technology because they bring enormous practicality to state-of-the-art achievements
Carbajo, Sergio +4 more
core +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, 2009 The production of highly energetic beams of both electrons and ions is a major part of the experimental programme at the Central Laser Facility (CLF), STFC Rutherford Appleton Laboratory. Every year sees a significant number of experiments done in both areas. This has been complemented by theoretical studies that have been carried out at the CLF and UK
Norreys, P, Robinson, A, Trines, R
openaire +3 more sources
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Lattice Design in High-energy Particle Accelerators
, 2014 This lecture gives an introduction into the design of high-energy storage ring lattices. Applying the formalism that has been established in transverse beam optics, the basic principles of the development of a magnet lattice are explained and the ...
Holzer, B. J.
core +1 more source
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
Charged Spinning Black Holes as Particle Accelerators
, 2010 It has recently been pointed out that the spinning Kerr black hole with maximal spin could act as a particle collider with arbitrarily high center-of-mass energy.
Fu, Chun-E +3 more
core +1 more source
Evaluation of the effect of metal stents on dose perturbation in the carbon beam irradiation field
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Propose Carbon ion therapy is indicated for cases in which stents have been inserted, such as bile ducts, but the effect of metal stents on carbon ion therapy is unclear. In this study, the dose perturbation of carbon ion therapy caused by metallic bile duct stents was evaluated by dosimetry. Materials and methods Five different types of metal
Yuya Miyasaka +8 more
wiley +1 more source
Weakly magnetized black holes as particle accelerators
, 2011 We study collision of particles in the vicinity of a horizon of a weakly magnetized non-rotating black hole. In the presence of the magnetic field innermost stable circular orbits (ISCO) of charged particles can be located close to the horizon.
D. V. Gal’tsov, Valeri P. Frolov
core +1 more source