Results 51 to 60 of about 1,288,945 (304)

Particle Accelerators in China

open access: yes, 2016
As the special machines that can accelerate charged particle beams to high energy by using electromagnetic fields, particle accelerators have been widely applied in scientific research and various areas of society.
Chuang Zhang, Shouxian Fang
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Applications of Particle Accelerators [PDF]

open access: yes
Of the tens of thousands of particle accelerators in operation worldwide, the vast majority are not used for particle physics, but instead for applications. Some applications such as radiotherapy for cancer treatment are well-known, while others are more
Sheehy, Suzie
core   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Particle Accelerators and Detectors for medical Diagnostics and Therapy [PDF]

open access: yes, 2013
This Habilitationsschrift (Habilitation thesis) is focused on my research activities on medical applications of particle physics and was written in 2013 to obtain the Venia Docendi (Habilitation) in experimental physics at the University of Bern.
Braccini, Saverio
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Introduction to particle accelerators [PDF]

open access: yes, 1992
A ten-lecture course on particle ...
Wilson, E J N, Wilson, Edmund J N
core  

Brief Introduction to Particle Accelerators

open access: yes, 2017
This lecture is a brief introduction to charged particle accelerators. The aim is to provide the reader with basic concepts and tools needed to describe the motion of charged particles under the action of guiding and focussing fields, with an emphasis on
Tavares, P. F.,, Lund University.
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Beam dynamics in high energy particle accelerators

open access: yes, 2014
Particle accelerators are essential tools for scientific research in fields as diverse as high energy physics, materials science and structural biology. They are also widely used in industry and medicine.
Wolski A, Wolski, Andrzej
core   +1 more source

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