Results 51 to 60 of about 69,476 (301)
Journal of Materials Research and Technology, 2022 Broken waste rock as backfill materials is filled into the underground goaf and will encounter particle breakage under the overburden pressure. The damage degree of the crushed waste rock materials directly affects the compression properties of the ...
Meng Li +4 more
doaj +1 more source
Investigation of railroad ballast particle breakage [PDF]
Pollack Periodica, 2019 Abstract This paper summarizes the authors' up-to-date results in the research topic of railway ballast particles' breakage test with individual laboratory test.
Juhász, Erika, Fischer, Szabolcs
openaire +2 more sources
Calculating the state parameter in crushable sands [PDF]
, 2019 The state parameter (y) measures the distance from the current state to the critical state line (CSL) in the compression plane. The existence of a correlation between both the peak angle of shearing resistance ( # $ ) and peak dilatancy and y is central ...
Ciantia, Matteo, O'Sullivan, Catherine
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Characteristics of Direct Shear and Particle Breakage of Pebble Gravel Materials
Geofluids, 2020 Particle size is an important factor affecting the Thermal-Hydraulic-Mechanical (THM) coupling behavior of graveled rock mass, especially for the shear mechanical properties.
Chenjie Hong +4 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Investigation of Breakage Probability of Irregularly Shaped Particles by Impact tests
KONA Powder and Particle Journal, 2014 The modelling of experimental distributions of breakage energy by compression and impact was carried out. In terms of our model, the part of the particle that is directly contacted with the stressing tool is admitted
Sergej Aman +4 more
doaj +1 more source
Triaxial compression tests on a crushable sand in dry and wet conditions [PDF]
, 2015 A calcareous sand from the Persian Gulf is subjected to a series of dry and fully drained saturated triaxial shear tests. The samples are prepared at relative densities of 65% and either left dry or saturated. They are consolidated to confining pressures
Haegeman, Wim, Van Impe, PO, Wils, L
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source