Results 101 to 110 of about 3,847,981 (341)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Early decay of Peccei–Quinn fermion and the IceCube neutrino events
Physics Letters B, 2016 IceCube observed high-energy neutrino flux in the energy region from TeV to PeV. The decay of a massive long-lived particle in the early universe can be the origin of the IceCube neutrino events, which we call an “early decay scenario.” In this paper, we
Yohei Ema, Takeo Moroi
doaj +1 more source
Global Biogeochemical Cycles, 2013 A closed eddy core in the Subantarctic Atlantic Ocean was fertilized twice with two tons of iron (as FeSO4), and the 300 km2 fertilized patch was studied for 39 days to test whether fertilization enhances downward particle flux into the deep ocean ...
Patrick Martin +14 more
semanticscholar +1 more source
Major role of particle fragmentation in regulating biological sequestration of CO2 by the oceans
Science, 2020 Breaking up is easy to do Sinking particles transport carbon to the seafloor, where they are buried in sediments and either provide food for benthic organisms or sequester the carbon they contain.
N. Briggs, G. Dall’Olmo, H. Claustre
semanticscholar +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
A mechanistic particle flux model applied to the oceanic phosphorus cycle
, 2014 The sinking and decomposition of particulate or- ganic matter are critical processes in the ocean's biological pump, but are poorly understood and crudely represented in biogeochemical models. Here we present a mechanistic par- ticle remineralization and
T. DeVries, Jun‐Hong Liang, C. Deutsch
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
A Study of the Correlation between Earthquakes and NOAA Satellite Energetic Particle Bursts
Remote Sensing, 2010 Over the last two decades, potentially interesting phenomena in the ionosphere-magnetosphere transition region have been studied; anomalous particle fluxes detected by several space experiments and correlated with earthquakes.
William J. Burger +2 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Jump at the onset of saltation
, 2011 We reveal a discontinuous transition in the saturated flux for aeolian saltation by simulating explicitly particle motion in turbulent flow. The discontinuity is followed by a coexistence interval with two metastable solutions.
G. H. Keulegan +11 more
core +1 more source