Results 71 to 80 of about 3,847,981 (341)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Particle-laden weakly swirling free jets: Measurements and predictions [PDF]
A theoretical and experimental investigation of particle-laden, weakly swirling, turbulent free jets was conducted. Glass particles, having a Sauter mean diameter of 39 microns with a standard deviation of 15 microns, were used. A single loading ratio of
Cosman A.D.. +10 more
core +2 more sources
Currents and flux-inversion in photokinetic active particles [PDF]
Travelling light patterns can transport light-driven active particles with a current that becomes negative for slow patterns.
Claudio Maggi +3 more
openaire +5 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A precision measurement by AMS of the antiproton flux and the antiproton-to-proton flux ratio in primary cosmic rays in the absolute rigidity range from 1 to 450 GV is presented based on 3.49×10^{5} antiproton events and 2.42×10^{9} proton events.
M. Aguilar +268 more
semanticscholar +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Statistics of Flux Vacua for Particle Physics
Supersymmetric flux compactification of F-theory in the geometric phase yields numerous vacua, and provides an ensemble of low-energy effective theories with different symmetry, matter multiplicity and Lagrangian parameters.
Watari, Taizan
core +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Spatiotemporal dynamics of snow erosion, deposition and horizontal mass flux
The quantification of snow transport, both in wind tunnels and the field, apply particle counting methods limited to punctual sampling of relatively small volumes. Particle counting can only capture horizontal mass fluxes, failing to measure snow erosion
PHILIP CRIVELLI +2 more
doaj +1 more source

