Results 201 to 210 of about 43,251,177 (344)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

A physical particle model of morphogenesis

open access: yes, 2003
This paper describes an evolutionary process which produces dynamic biologic-like patterns. Simulation and visualization of the development of cell populations has many applications. For example, developmental biology and computer graphics. Physically-based particle models are efficient to simulate the dynamical behavior of real life objects.
Boulenguez, Pierre, Luciani, Annie
openaire   +3 more sources

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The particle system model of income and wealth more likely to imply an analogue of thermodynamics in social science [PDF]

open access: yes
The Inequality Process (IP) and the Saved Wealth Model (SW) are particle system models of income distribution. The IP’s social science meta-theory requires its stationary distribution to fit the distribution of labor income conditioned on education.
Angle, John
core  

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