Results 51 to 60 of about 542,620 (267)
Modeling on Effect of Particle Sediment on Fluid Flow and Heat Transfer of Solid–Fluid Suspension
A two-way coupling particle flux model is proposed for studying the multi-component solid–fluid suspension. The suspension mixture is treated as a non-linear single-phase fluid and the migration of the solid particles is modeled by a particle flux ...
Yan Wu, Wei-Tao Wu
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Numerical Modeling of Reinforcement Solutions in Traditional Stone Masonry Using a Particle Model
Traditional stone masonry walls are structural elements in most historic buildings. To preserve them and improve their ability to withstand extreme events, such as earthquakes, it is necessary to implement effective reinforcement solutions.
Nuno Monteiro Azevedo +3 more
doaj +1 more source
Particle Filters for Graphical Models
This paper discloses a novel algorithm for efficient inference in undirected graphical models using Sequential Monte Carlo (SMC) based numerical approximation techniques. The developed methodology extends the applicability of the much celebrated Loopy Belief Propagation (LBP) algorithm to nonlinear, non-Gaussian models, whilst retaining a computational
Briers, M +3 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Particle production beyond the thermal model
The sources of particle production in relativistic heavy-ion collisions are investigated from RHIC to LHC energies. Whereas charged-hadron production in the fragmentation sources follows a ln(sNN/s0) law, particle production in the mid-rapidity low-x ...
Wolschin Georg
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The Development of Theoretical Basis of Mathematical Model of Crushed Rock Particle-Particle Packing [PDF]
The existing mathematical models that predict the poly-fractional granular media packing density do not take into account their packing degree, which gives a fairly large deviation of the simulation results from the actual experimental values (up to 20 ...
Shabaev Sergey +2 more
doaj +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

