Results 241 to 250 of about 22,766 (290)
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
Advanced Science, EarlyView.ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa +13 morewiley +1 more sourceEndoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability
Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov +13 morewiley +1 more sourceStudy of Free‐Space Optical Quantum Network: Review and Prospectives
Advanced Science, EarlyView.Free from the constraints of fiber connections, free‐space quantum network enables longer and more flexible quantum network connections. This review summarizes and comparatively analyzes free‐space quantum network experiments based on ground stations, satellites, and mobile platforms.Hua‐Ying Liu, Zhenda Xie, Shining Zhuwiley +1 more sourceUltrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis
Advanced Science, EarlyView.This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen +7 morewiley +1 more sourceUltrahigh-energy gamma-ray emission associated with black hole-jet systems. [PDF]
Natl Sci RevCao Z, Aharonian F, Bai YX, Bao YW, Bastieri D, Bi XJ, Bi YJ, Bian WY, Bukevich AV, Cai C, Cao WY, Cao Z, Chang J, Chang JF, Chen A, Chen ES, Chen G, Chen HX, Chen L, Chen L, Chen MJ, Chen ML, Chen QH, Chen S, Chen SH, Chen SZ, Chen TL, Chen XB, Chen X, Chen Y, Cheng N, Cheng YD, Chu MC, Cui MY, Cui SW, Cui XH, Cui YD, Dai BZ, Dai HL, Dai Z, Luobu D, Diao YX, Dong XQ, Duan KK, Fan JH, Fan YZ, Fang J, Fang JH, Fang K, Feng CF, Feng H, Feng L, Feng S, Feng XT, Feng Y, Feng YL, Gabici S, Gao B, Gao CD, Gao Q, Gao W, Gao WK, Ge M, Ge TT, Geng L, Giacinti G, Gong G, Gou Q, Gu MH, Guo FL, Guo J, Guo XL, Guo YQ, Guo YY, Han YA, Hannuksela OA, Hasan M, He HH, He HN, He JY, He X, He Y, Hernández-Cadena S, Hou BW, Hou C, Hou X, Hu HB, Hu SC, Huang C, Huang DH, Huang J, Huang TQ, Huang WJ, Huang XT, Huang XY, Huang Y, Huang YY, Ji XL, Jia HY, Jia K, Jiang HB, Jiang K, Jiang XW, Jiang ZJ, Jin M, Kaci S, Kang MM, Karpikov I, Khangulyan D, Kuleshov D, Kurinov K, Li BB, Li C, Li C, Li D, Li F, Li H, Li H, Li J, Li J, Li K, Li L, Li RL, Li SD, Li TY, Li WL, Li XR, Li X, Li Y, Li Y, Li Z, Li Z, Liang EW, Liang YF, Lin SJ, Liu B, Liu C, Liu D, Liu DB, Liu H, Liu HD, Liu J, Liu JL, Liu JR, Liu MY, Liu RY, Liu SM, Liu W, Liu X, Liu Y, Liu Y, Liu YN, Lou YQ, Luo Q, Luo Y, Lv HK, Ma BQ, Ma LL, Ma XH, Mao JR, Min Z, Mitthumsiri W, Mou GB, Mu HJ, Neronov A, Ng KCY, Ni MY, Nie L, Ou LJ, Pattarakijwanich P, Pei ZY, Qi JC, Qi MY, Qin JJ, Raza A, Ren CY, Ruffolo D, Sáiz A, Semikoz D, Shao L, Shchegolev O, Shen YZ, Sheng XD, Shi Z, Shu FW, Song HC, Stenkin YV, Stepanov V, Su Y, Sun D, Sun H, Sun Q, Sun X, Sun Z, Tabasam NH, Takata J, Tam PHT, Tan HB, Tang Q, Tang R, Tang Z, Tian W, Tong C, Wan LH, Wang C, Wang G, Wang H, Wang J, Wang K, Wang K, Wang L, Wang L, Wang LY, Wang R, Wang W, Wang X, Wang XJ, Wang XY, Wang Y, Wang YD, Wang ZH, Wang ZX, Wang Z, Wei DM, Wei JJ, Wei YJ, Wen T, Weng SS, Wu CY, Wu HR, Wu QW, Wu S, Wu XF, Wu YS, Xi SQ, Xia J, Xia JJ, Xiang GM, Xiao DX, Xiao G, Xin YL, Xing Y, Xiong DR, Xiong Z, Xu DL, Xu RF, Xu RX, Xu WL, Xue L, Yan DH, Yan JZ, Yan T, Yang CW, Yang CY, Yang FF, Yang LL, Yang MJ, Yang RZ, Yang WX, Yang Z, Yao ZG, Ye XA, Yin LQ, Yin N, You XH, You ZY, Yu YH, Yuan Q, Yue H, Zeng HD, Zeng TX, Zeng W, Zeng X, Zha M, Zhang BB, Zhang BT, Zhang C, Zhang F, Zhang HF, Zhang HM, Zhang HY, Zhang JL, Zhang L, Zhang PF, Zhang PP, Zhang R, Zhang SR, Zhang SS, Zhang W, Zhang X, Zhang XP, Zhang Y, Zhang Y, Zhang ZP, Zhao J, Zhao L, Zhao LZ, Zhao SP, Zhao XH, Zhao Z, Zheng F, Zhong WJ, Zhou B, Zhou H, Zhou JN, Zhou M, Zhou P, Zhou R, Zhou XX, Zhou XX, Zhu BY, Zhu CG, Zhu FR, Zhu H, Zhu KJ, Zou YC, Zuo X. +316 moreeuropepmc +1 more sourceGHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu +24 morewiley +1 more source
