Results 151 to 160 of about 3,316,013 (300)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Advancements in Understanding Interface Friction: A Combined Experimental and Machine Learning Approach Using Multiple Linear and Random Forest Regressions

open access: yesGeotechnics
The interface friction between granular materials and continuum surfaces is fundamental in civil engineering, especially in geotechnical projects where sand of varying sizes and shapes contacts surfaces with different roughness and hardness.
Firas Daghistani, Hossam Abuel-Naga
doaj   +1 more source

The effect of particle shape on discharge and clogging. [PDF]

open access: yesSci Rep, 2021
Hafez A   +5 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Particle shape quantification using rotation-invariant spherical harmonic analysis

open access: yes, 2017
A three-dimensional particle surface can be mathematically represented by a spherical harmonic (SH) coefficient matrix through surface parameterisation and SH expansion.
J. F. Wang, D. H. Wei, B. D. Zhao
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

How particle shape affects battery performance

open access: yes
Particle morphology (i.e. size and shape) plays a critical role in determining the microstructure and performance of battery electrodes, however, the influence of particle shape remains underexplored compared to particle size or composition.
Loxley, Neil   +4 more
core   +1 more source

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