Results 131 to 140 of about 1,114,868 (291)

Impact of Particle Shape and Surface Group on Membrane Fouling. [PDF]

Membranes (Basel), 2022
Tanis-Kanbur MB, Tamilselvam NR, Lai HY, Chew JW.   +3 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The effect of particle shape on discharge and clogging. [PDF]

Sci Rep, 2021
Hafez A, Liu Q, Finkbeiner T, Alouhali RA, Moellendick TE, Santamarina JC.   +5 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aspherical, Nano-Structured Drug Delivery System with Tunable Release and Clearance for Pulmonary Applications

Pharmaceutics
Addressing the challenge of efficient drug delivery to the lungs, a nano-structured, microparticulate carrier system with defined and customizable dimensions has been developed.
Tomas Pioch, Thorben Fischer, Marc Schneider   +2 more
doaj   +1 more source

Efficient solution of particle shape functions for the analysis of powder total scattering data. [PDF]

J Appl Crystallogr, 2022
Leonardi A, Neder R, Engel M.
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Assembling Biocompatible Polymers on Gold Nanoparticles: Toward a Rational Design of Particle Shape by Molecular Dynamics. [PDF]

ACS Omega, 2022
Cappabianca R, De Angelis P, Cardellini A, Chiavazzo E, Asinari P.   +4 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Synthesis of Hydrophobic Nanosized Silicon Dioxide with a Spherical Particle Shape and Its Application in Fire-Extinguishing Powder Compositions Based on Struvite. [PDF]

Nanomaterials (Basel), 2023
Valtsifer IV, Huo Y, Zamashchikov VV, Shamsutdinov AS, Kondrashova NB, Sivtseva AV, Pyankova AV, Valtsifer VA.   +7 more
europepmc   +1 more source