Experimental study on influence of particle shape on shockwave from collapse of cavitation bubble. [PDF]
Zou L +6 more
europepmc +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Interactive Introduction to Shape Machine
Presented as part of the Shape Machine Symposium on April 11, 2019 at 9:10 a.m. in the John & Joyce Caddell Building, Flex Space.Athanassios (Thanos) Economou is Professor in the College of Design at Georgia Institute of Technology.
Economou, Athanassios +1 more
core
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Abradable DEM: A Novel Framework to Capture the Mechanistic Evolution of Particle Shape
Although various methods exist for modelling non-spherical particles in DEM, particles’ shapes are usually treated as immutable. However, particles often change shape gradually, e.g., due to abrasion or accrued plastic deformation.
Rogan, Haydn
core +1 more source
Calculating Shape Factors from Particle Sizing Data
It is well established that particle size and shape substantially influence the bulk properties of powdered materials. Although these characteristics are closely interrelated, the tendency has been to analyse the particle size independently from particle
Barreiros, Fátima M. +5 more
core +1 more source
Wrapping anisotropic microgel particles in lipid membranes: Effects of particle shape and membrane rigidity. [PDF]
Liu X +8 more
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
The Effect of Particle Shape on the Compaction of Realistic Non-Spherical Particles-A Multi-Contact DEM Study. [PDF]
Giannis K, Kwade A, Finke JH, Schilde C.
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source

