Results 141 to 150 of about 3,316,013 (300)
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Wrapping anisotropic microgel particles in lipid membranes: Effects of particle shape and membrane rigidity. [PDF]
Proc Natl Acad Sci U S A, 2023 Liu X +8 more
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
The Effect of Particle Shape on the Compaction of Realistic Non-Spherical Particles-A Multi-Contact DEM Study. [PDF]
Pharmaceutics, 2023 Giannis K, Kwade A, Finke JH, Schilde C.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Influence of Magnet Particle Shape on Magnetic and Environmental Stability of FDM Polymer-Bonded Magnets. [PDF]
Materials (Basel), 2023 Damnjanović A, Kovačević N.
europepmc +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Impact of Particle Shape and Surface Group on Membrane Fouling. [PDF]
Membranes (Basel), 2022 Tanis-Kanbur MB +3 more
europepmc +1 more source
Tuning and test of fragmentation models based on identified particles and precision event shape data
, 1996 CERN-LEP. Measurement of event-shape and charged particle inclusive distributions in 750000 decays of the Z0 to ...
Parkes, Christopher; id_orcid +2 more
core +1 more source