Results 51 to 60 of about 246,503 (260)

Performance Parameters and Characterizations of Nanocrystals: A Brief Review

Pharmaceutics, 2016
Poor bioavailability of drugs associated with their poor solubility limits the clinical effectiveness of almost 40% of the newly discovered drug moieties.
Manasi M. Chogale, Vinod N. Ghodake, Vandana B. Patravale   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Improved Metaball Discrete Element Method with Robust Contact Algorithm for General-Shaped Particles with Rounded Features

Applied Sciences
Particle shape is a critical factor governing the macroscopic behavior of granular materials. While the Discrete Element Method (DEM) has proven to be a powerful tool for modeling these materials, the accurate representation of particles with realistic ...
Pei Zhang, Songkai Ren, Can Fu, Cheng Cheng, S. A. Galindo-Torres, Rong Lan   +5 more
doaj   +1 more source

Particle Shape Effect on Macroscopic Behaviour of Underground Structures: Numerical and Experimental Study

Studia Geotechnica et Mechanica, 2015
The mechanical performance of underground flexible structures such as buried pipes or culverts made of plastics depend not only on the properties of the structure, but also on the material surrounding it.
Szarf Krzysztof, Combe Gael, Villard Pascal   +2 more
doaj   +1 more source

Effect of Particle Size and Constraint Conditions on Single Particle Strength of Carbonate Sand

Sensors, 2022
Carbonate sand is often encountered and utilized as construction material in offshore engineering projects. Carbonate sand particles, which are porous and angular, are found to be highly crushable under high stress conditions, whereas the mechanisms and ...
Yong He, Guojun Cai, Lei Gao, Huan He
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Particle Shape [PDF]

Nature, 1945
  +7 more sources

Discrete element modeling of non-spherical particles using a spherical shape

REM: International Engineering Journal, 2020
Real non-spherical particles can be modeled using the Discrete Element Method (DEM) with sphere clusters, superquadrics, or polyhedral particles. However, in applications involving a considerable number of particles, the analysis can become impracticable.
Elias Gomes Santos, Luiz Carlos da Silva Carvalho, André Luiz Amarante Mesquita, Luiz Moreira Gomes, Kelvin Alves Pinheiro, Alexandre Luiz Amarante Mesquita   +5 more
doaj   +1 more source

High Fluid Velocity and Narrow Channels Enhance the Influences of Particle Shape on Colloid Retention in Saturated Groundwater Systems Under Favorable Deposition Conditions

Frontiers in Water, 2021
Many particulate pollutants in the environment exist in non-spherical shape, but the influences of particle shape on pollutant migration and removal in groundwater systems are not well-understood.
Ke Li, Huilian Ma
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source