Results 101 to 110 of about 291,283 (307)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Shape-Anisotropic Diblock Copolymer Particles from Evaporative Emulsions: Experiment and Theory
, 2019 Self-assembly of block copolymers (BCPs) in evaporative emulsion provides a simple and effective route for the preparation of anisotropic particles with controlled shape and size.
Bumjoon J. Kim (1477771) +7 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Super-resolution Pulsed Magnetic Particle Imaging Using Shape Anisotropic Nanoparticles
Pulsed magnetic particle imaging (MPI) allows the use of long relaxation time magnetic particles to achieve high-resolution images. In this study, we proposed a super-resolution imaging method for pulsed MPI, which can further enhance its spatial ...
Wang, Zhongliang +4 more
core +1 more source
Shape-Dependent Motion of Structured Photoactive Microswimmers
, 2018 We investigate the dynamics of structured photoactive microswimmers and show that morphology sensitively determines the swimming behavior. Particular to this study, a major portion of the light-activated particles’ underlying structure is built from a ...
John Castañeda (5219177) +9 more
core +2 more sources
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Metal particle shape: A practical perspective
, 2018 The choice of appropriate processing conditions in powder metallurgy and the achievement of the required properties for the final metal components greatly depend on the shape of the solid phase.
Sola A. +3 more
core +1 more source
Effects of concentration of dispersions on particle sizing during production of fine particles in wet grinding process [PDF]
, 2011 Stirred media milling is a prospective technology for producing colloidal dispersions by means of wet grinding process. In the past, many researchers have studied the effects of different operating parameters such as size, shape, nature and quantity of ...
Frances, Christine +5 more
core +1 more source
Shape of Small Particles [PDF]
Nature, 1964 I REGRET that the index 2 was omitted from one of the β's in the denominator of equation (19) in my article published in Nature under the above title1; this was due to an error in the analysis which escaped me and was later detected by Mr. J. Cartwright of the Safety in Mines Research Establishment when applying the method to coal dust.
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source