Results 81 to 90 of about 6,010,535 (335)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The distribution of settling velocity of non-spherical mineral particles [PDF]

open access: yesActa Montanistica Slovaca, 2005
The settling velocity is an independent variable of the hydraulic separation performed for instance by means of jigs. Therefore, the settling velocity characterizes the material forwarded to the separation process.
Marian Brožek, Agnieszka Surowiak
doaj  

Bedload transport in rivers, size matters but so does shape

open access: yesScientific Reports, 2021
Bedload transport modelling in rivers takes into account the size and density of pebbles to estimate particle mobility, but does not formally consider particle shape.
Mathieu Cassel   +4 more
doaj   +1 more source

Shape of Small Particles [PDF]

open access: yesNature, 1964
I REGRET that the index 2 was omitted from one of the β's in the denominator of equation (19) in my article published in Nature under the above title1; this was due to an error in the analysis which escaped me and was later detected by Mr. J. Cartwright of the Safety in Mines Research Establishment when applying the method to coal dust.
openaire   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Shear strength of angular granular materials with size and shape polydispersity

open access: yesOpen Geomechanics
Shear strength characterization of coarse granular materials often requires modifying the original material in order to fit samples in standard testing devices.
Sergio Andres Carrasco Cisterna   +3 more
doaj   +1 more source

Simulating three dimensional self-assembly of shape modified particles using magnetic dipolar forces [PDF]

open access: yes, 2011
The feasibility of 3D self-assembly of milli-magnetic particles that interact via magnetic dipolar forces is investigated. Typically magnetic particles, such as isotropic spheres, self-organize in stable 2D configurations.
Abelmann, Leon   +3 more
core   +1 more source

Models for Metal Hydride Particle Shape, Packing, and Heat Transfer

open access: yes, 2012
A multiphysics modeling approach for heat conduction in metal hydride powders is presented, including particle shape distribution, size distribution, granular packing structure, and effective thermal conductivity.
Asakuma   +49 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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