Results 31 to 40 of about 2,195,420 (349)
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Many cities in China are facing the dual challenge of PM2.5 and PM10 pollution. There is an urgent need to develop a cost-effective method that can apportion both with high-time resolution.
Peizhi Wang +9 more
doaj +1 more source
Powder Technology and Pharmaceutical Development: Particle Size and Particle Adhesion
Both the FDA (U.S. Food and Drug Administration) and ICH (International Conference on Harmonisation) have urged the incorporation of Quality by Design (QbD)1) into the manufacture of pharmaceutical products2).The performance of many pharmaceutical ...
Frank M. Etzler, Mohammad Nasir Uddin
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
An Insight Analysis of Nano sized powder of Jackfruit Seed
The preparation of biodegradable nanomaterials by blending starch nanocrystals with various polymer matrices are the most active research. This work reports aspect related to nano-sized particles of jackfruit seed.
Alagar, M., Theivasanthi, T.
core +1 more source
Effects of concentration of dispersions on particle sizing during production of fine particles in wet grinding process [PDF]
Stirred media milling is a prospective technology for producing colloidal dispersions by means of wet grinding process. In the past, many researchers have studied the effects of different operating parameters such as size, shape, nature and quantity of ...
Frances, Christine +2 more
core +2 more sources
Influence of Mie scattering on nanoparticles with different particle sizes and shapes: photometry and analytical ultracentrifugation with absorption optics [PDF]
Nanoparticles are used in large quantities for very different applications. A precise determination of the diameter and the particle size distribution which is responsible for the application properties is therefore essential.
M. D. LECHNER
doaj +3 more sources
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Conditional stability of particle alignment in finite-Reynolds-number channel flow
Finite-size neutrally buoyant particles in a channel flow are known to accumulate at specific equilibrium positions or spots in the channel cross-section if the flow inertia is finite at the particle scale.
Abbas, Micheline +3 more
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source

