Results 41 to 50 of about 813,177 (264)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Activation temperature and particle size of palm kernel shell vs. the surface properties of activated carbon

open access: yes, 2023
Granular activated carbon (GAC) and powdered activated carbon (PAC) are the two most common forms of activated carbon with varying particle size range.
Khoo, Pui San   +4 more
core   +1 more source

Effect of Particle Shape on Size Segregation of Particles

open access: yesChemical Engineering Transactions, 2013
High-level control of the particle packing structure in a container requires the detailed analysis of particle size segregation during gravity filling. Here, we propose a method for analyzing quantitatively the effect of particle shape on the size segregation of particles using DEM (Distinct Element Method) simulation, which employ spherical particles ...
Atsuko Shimosaka   +3 more
openaire   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

particle size

open access: yes, 2014
Citation: 'particle size' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.P04430 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +2 more sources

Uniformity of Size of Bacteriophage Particles

open access: yesExperimental Biology and Medicine, 1947
SummaryNeither fractional ultrafiltration nor fractional centrifugation have revealed any heterogeneity of size among the particles of the bacteriophage T2K (formerly called PC). The methods used for the measurement of size, namely, diffusion through agar and sedimentation in an angle centrifuge, were essentially qualitative.
A D, HERSHEY   +2 more
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Method for Particle Size Control During the Drying and Granulation in Fluidized Bed

open access: yes, 2001
The fluidized bed process presented in this paper is suitable for recovery of solids from solutions in the form of granules. The solution is sprayed into the bed and as solvent evaporates, solid material is deposited on the surface of fluidizing ...
Gyenis, János, Dencs, B., Tardos, I. G.
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Particle Size Control by Torque Measurements in Fluidized Beds during Drying and Granulation from Solutions

open access: yes, 2001
The fluidized bed process presented in this paper is suitable to recover solids from solution in form of granules. Solution is sprayed into the bed and, as the solvent evaporates, solid material is deposited on the surface of fluidizing particles ...
Gyenis, János, Dencs, B., Tardos, I. G.
core  

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