Results 61 to 70 of about 2,155,826 (293)

Particle diffusion in active fluids is non-monotonic in size [PDF]

open access: yes, 2015
We experimentally investigate the effect of particle size on the motion of passive polystyrene spheres in suspensions of Escherichia coli. Using particles covering a range of sizes from 0.6 to 39 microns, we probe particle dynamics at both short and long
Arratia, Paulo E.   +3 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Analysis and Application of Particle Backtracking Algorithm in Wind–Sand Two-Phase Flow Using SPH Method

open access: yesApplied Sciences
Due to the high sensitivity of grid-based micro-scale wind–sand flow models to deformation and distortion, this study employs the Smooth Particle Hydrodynamics (SPH) method for numerical simulations.
Wenxiu Gao   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Sheathless Size-Based Acoustic Particle Separation

open access: yesSensors, 2012
Particle separation is of great interest in many biological and biomedical applications. Flow-based methods have been used to sort particles and cells. However, the main challenge with flow based particle separation systems is the need for a sheath flow ...
Jiang Zhe   +4 more
doaj   +1 more source

A unified analysis of nano-to-microscale particle dispersion in tubular blood flow

open access: yes, 2019
Transport of solid particles in blood flow exhibits qualitative differences in the transport mechanism when the particle varies from nanoscale to microscale size comparable to the red blood cell (RBC).
Aidun, Cyrus K.   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

ESTIMATING SOIL PARTICLE-SIZE DISTRIBUTION FOR SICILIAN SOILS

open access: yesJournal of Agricultural Engineering, 2009
The soil particle-size distribution (PSD) is commonly used for soil classification and for estimating soil behavior. An accurate mathematical representation of the PSD is required to estimate soil hydraulic properties and to compare texture measurements ...
Vincenzo Bagarello   +2 more
doaj   +1 more source

Adiponectin and Lipoprotein Particle Size

open access: yesDiabetes Care, 2009
OBJECTIVE Adiponectin has been postulated to affect lipid and insulin signal transduction pathways. We evaluated the relationships of plasma adiponectin with lipoprotein mean particle size and subclass concentrations, independent of obesity and insulin sensitivity ...
Weiss, Ram   +6 more
openaire   +2 more sources

Effects of the finite particle size in turbulent wall-bounded flows of dense suspensions

open access: yes, 2018
We use interface-resolved simulations to study finite-size effects in turbulent channel flow of neutrally-buoyant spheres. Two cases with particle sizes differing by a factor of 2, at the same solid volume fraction of 20% and bulk Reynolds number are ...
Brandt, Luca   +3 more
core   +1 more source

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