Results 61 to 70 of about 5,670,228 (254)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Simulations of spatial variability in particle-size emissions during wind erosion events
, 2012 This study simulates how spatial variations in particle-size emissions from a playa affect bulk and size-resolved dust concentration profiles during two contrasting wind erosion events (a small local and a large regional event) in the Channel Country ...
Butler, Harry J +5 more
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Applied SciencesDue to the high sensitivity of grid-based micro-scale wind–sand flow models to deformation and distortion, this study employs the Smooth Particle Hydrodynamics (SPH) method for numerical simulations.
Wenxiu Gao +3 more
doaj +1 more source
, 2004 This biennial Review summarizes much of Particle Physics. Using data from previous editions, plus 1726 new measurements from 512 papers, we list, evaluate, and average measured properties of gauge bosons, leptons, quarks, mesons, and baryons.
Particle Data Group, Particle Data Grp
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Sheathless Size-Based Acoustic Particle Separation
Sensors, 2012 Particle separation is of great interest in many biological and biomedical applications. Flow-based methods have been used to sort particles and cells. However, the main challenge with flow based particle separation systems is the need for a sheath flow ...
Jiang Zhe +4 more
doaj +1 more source
, 2017 Size-frequency-distributions (gel particle-bacteria and gel particle-gel particle) at western AWI HAUSGARTEN in 2015 (CTD, PS93/058-8 and PS93/058 ...
Iversen, Morten Hvitfeldt +11 more
core +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source