Results 71 to 80 of about 2,155,826 (293)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Moment Dynamics of Zirconia Particle Formation for Optimizing Particle Size Distribution
We study the particle formation process of Zirconia ( ZrO 2 )-based material. With a model-based description of the particle formation process we aim for identifying the main growth mechanisms for different process parameters.
Wolfgang Halter +4 more
doaj +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Boson star with particle size effects
A simple model to study boson stars is to consider these stellar objects as quantum systems of $N$ identical self-gravitating particles within a non-relativistic framework.
Semay, C.
core
Towards a complete inventory of stratospheric dust particles, with implications for their classification [PDF]
Several investigators have recently proposed classification schemes for stratospheric dust particles [1-3]. In addition, extraterrestrial materials within stratospheric dust collections may be used as a measure of micrometeorite flux [4]. However, little
Mackinnon, Ian D.R. +2 more
core +1 more source
Computational analysis of shock-induced flow through stationary particle clouds
We investigate the shock-induced flow through random particle arrays using particle-resolved Large Eddy Simulations for different incident shock wave Mach numbers, particle volume fractions and particle sizes.
Omang, Marianne Gjestvold +3 more
core +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
SUCELL Test Conditions Optimization of HELOS/BF Laser Particle Size Analyzer
The Laser Particle Size Analyzer is being more widely used due to its fast test speed, convenient operation and good repeatability, to name a few of its qualities.
LU Xin-cheng, CAO Jing-yang
doaj

