Results 91 to 100 of about 5,670,228 (254)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Large-Scale Candidate Gene Analysis of HDL Particle Features [PDF]

open access: yes, 2011
Background: HDL cholesterol (HDL-C) is an established marker of cardiovascular risk with significant genetic determination. However, HDL particles are not homogenous, and refined HDL phenotyping may improve insight into regulation of HDL metabolism.
Burton Paul R.   +105 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Particle size distribution of dried sewage sludge

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012
The aim of this paper was to determine the basic granulometric curves related to the dried sewage sludge and particles size distribution according to Rosin-Rammler, which belongs to the most widely used methods for the statistical distribution of ...
Radovan Kukla   +2 more
doaj   +1 more source

A new apparatus for recording particle size distribution

open access: yes, 1968
A manometer and sensitive capacitance transducer follow the drop in hydrostatic pressure at a point near the bottom of a column of soil suspension during sedimentation.
Bascomb, C. L.
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Magnetic particle grinding and finishing test of mixed particle size abrasives

open access: yesJin'gangshi yu moliao moju gongcheng
ObjectivesMagnetic particle grinding finishing technology as an advanced processing technology can achieve high precision surface treatment. In order to simplify the test device, reduce the test cost and improve the processing effect, the single particle
Bingyang LIU   +4 more
doaj   +3 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Particle-Size-Dependent Electronic Metal–Support Interaction in Pd/TiO2 Catalysts for Selective Hydrogenation of 3‑Nitrostyrene

open access: yes
The Pd/TiO2 catalysts with varying Pd nanoparticle sizes are used to study the control of selectivity toward the hydrogenation of 3-nitrostyrene (3-NS).
Junhong Fu (1902589)   +5 more
core   +1 more source

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