Results 101 to 110 of about 5,670,228 (254)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Characteristics of Spatial Distribution of Surface Soil Particle Size in Qingtu Lake at the End of Shiyang River

open access: yesShuitu baochi yanjiu
[Objective]The aims of this study are to reveal the characteristics of spatial distribution of soil grain size in Qingtu Lake at the end of Shiyang River, and to provide theoretical basis for ecological restoration in this region. [Methods]Sampling lines
An Fubo   +6 more
doaj  

Particle Size Effects in Fischer-Tropsch Synthesis by Cobalt

open access: yes, 2011
Particle Size Effects in Fischer-Tropsch Synthesis by ...
D.WayneGoodman   +3 more
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Influence of particle size in silo discharge

open access: yesEPJ Web of Conferences, 2017
Recently Janda et al. [Phys. Rev. Lett. 108, 248001 (2012)] reported an experimental study where it was measured the velocity and volume fraction fields of 1 mm diameter stainless steel beads in the exit of a two-dimensional silo.
Gella Diego, Maza Diego, Zuriguel Iker
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Size Effect of Sandstone Particle Crushing Strength and Aggregate Shear Strength Based on Nominal Particle Size

open access: yesRenmin Zhujiang
Single particle and particle assembly are subjected to uniaxial compression tests and direct shear tests to explore the strength characteristics under different sizes, stone contents, and maximum particle sizes.
QIU Zhenfeng   +5 more
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Dependence of thermal diffusivity on particle size in Au nano-fluid [PDF]

open access: yes, 2010
In this paper we report the measurement of thermal diffusivity of gold nanofluid prepared by γ-radiation with various particle sizes ranging from 7.0 nm to 18.7 nm. The thermal lens technique is used to measure thermal diffusivity of gold nano-fluid.
Mahdi, Mohd Adzir   +7 more
core   +1 more source

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