Results 61 to 70 of about 27,349 (293)

Calibration of Micromechanical Parameters for the Discrete Element Simulation of a Masonry Arch using Artificial Intelligence

Infrastructures, 2023
This study focuses on an old but still unresolved problem of automatically calibrating the constitutive parameters of discrete element models. Instead of the troublesome and time-consuming manual trial-and-error method, which is typical today, the ...
Ghulam Kibriya, Ákos Orosz, János Botzheim, Katalin Bagi   +3 more
doaj   +1 more source

Algorithms Applied to Global Optimisation – Visual Evaluation [PDF]

, 2012
Evaluation and assessment of various search and optimisation algorithms is subject of large research efforts. Particular interest of this study is global optimisation and presented approach is based on observation and visual evaluation of Real-Coded ...
Penev, Kalin
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Comparative analysis of evolutionary algorithms for optimising proportional–integral–derivative control in direct current motor speed regulation: A statistical evaluation

Journal of Algorithms & Computational Technology
Effective proportional–integral–derivative controller tuning is critical for attaining high-performance operation in direct current motor systems, especially when traditional approaches fail under nonlinear or uncertain dynamics.
Oluwaseun O. Martins, Christiaan C. Oosthuizen, Dawood A. Desai   +2 more
doaj   +1 more source

A novel methodology to predict monthly municipal water demand based on weather variables scenario

Journal of King Saud University: Engineering Sciences, 2022
This study provides a novel methodology to predict monthly water demand based on several weather variables scenarios by using combined techniques including discrete wavelet transform, principal component analysis, and particle swarm optimisation.
Salah L. Zubaidi, Khalid Hashim, Saleem Ethaib, Nabeel Saleem Saad Al-Bdairi, Hussein Al-Bugharbee, Sadik Kamel Gharghan   +5 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

A polar coordinate particle swarm optimiser [PDF]

Applied Soft Computing, 2011
The Particle Swarm Optimisation (PSO) algorithm consists of a population (or swarm) of particles that are ''flown'' through an n-dimensional space in search of a global best solution to an optimisation problem. PSO operates in Cartesian space, producing Cartesian solution vectors.
Wiehann Matthysen, Andries P. Engelbrecht   +1 more
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

PAPR reduction in OFDM using scaled particle swarm optimisation based partial transmit sequence technique

The Journal of Engineering, 2019
Partial transmit sequence (PTS) is one of the effective techniques for reducing the peak-to-average power ratio (PAPR) in orthogonal frequency division multiplexing (OFDM) systems. PTS technique has some issues such as higher computational complexity due
Sanjana Prasad, Ramesh Jayabalan, Ramesh Jayabalan   +2 more
doaj   +1 more source